Chapter 20-Blood Flashcards Preview

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Flashcards in Chapter 20-Blood Deck (41)
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-all blood cells are derived from a pluripotent stemm cell
--all cells except lymphocytes are derived from the resulting myeloid tissue
- in adults, all new blood cells are produced in the bone marrow
--liver and spleen contribute while in utero, but eventually cease



-formation of RBCs
-RBCs have no nucleus of mitochondria
-wear and tear with no repair
-RBCs last for about 120 days
-replace about 1% per day
-3 million RBCs replaced per second



-formation of WBCs
-granulocytes complete their development in the red marrow
--neutrophils last for 12 hours, dyeing after they engulf an object
-monocytes do no complete development until they exit the circulatory system
--immature cells can stay in bone marrow or move to thymus
-move to the spleen, tonsils, or lymph nodes where they mature
-can last for several years


blood type

RBC plasmalemma (cell membrane) has surface antigens
-these are usually glycoproteins or glycolipids
-are genetically determined (similar within ethnicities)
-A, B, and Rh are used to determine blood types


types of blood

A, B, AB, O
-people may have a antigens, b antigens, both (ab) and neither (o)
-you will produce antibody for all the antigens you dont have
-if foreign antigens are introduced into your bloodstream, you will produce antibodies to destroy them


Ab patient

can receive any blood, produces neither antibody


a patient

can receive blood from a and o, but produces B antibodies


b patients

can receive blood from b and o, but produces a antibodies


o patient

can receive blood from o only. produces a and b antibodies


Rh group

named after Rhesus macaque
-if you have rh antigen
--you are Rh+
-if you have no antigen
--you are Rh-
sometimes referred to as the D antigen


Rh group

Rh- people will only produce antibodies when exposed to the Rh antigen
--usually occurs from:
-receive Rh+ transfusion
-pregnant with Rh+ baby
--an Rh- mother may reject a second Rh+ baby