Chapter 7 Flashcards

(47 cards)

1
Q

Two parts of autonomic nervous system

A

Sympathetic and Parasympathetic

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2
Q

What part of autonomic nervous system is excitatory to targets and increases cellular functions?

A

Sympathetic nervous system

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3
Q

What part of autonomic nervous system is inhibitory to targets and decreases cellular functions?

A

Parasympathetic nervous system

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4
Q

Axon of pre synaptic to dendrites of post synaptic cell

A

Ganglion

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5
Q

Region sympathetic occurs at

A

Thoraco-lumbar

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6
Q

Region parasympathetic occurs at

A

Cranial-Sacral

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7
Q

Receptor that binds Ach

A

Cholerinic

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8
Q

Cholerinic receptor with Na+ channels, located on post ganglionic neurons

A

Nicotinic Receptor

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9
Q

Cholerinic receptor, changes second messengers, reduction/inhibition of specific cellular function

A

Muscarinic Receptor

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10
Q

Post ganglionic cells release this onto target for sympathetic nervous system

A

Norepinephrine (NE)

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11
Q

Post ganglionic cells release this onto target for parasympathetic nervous system

A

Acetylcholine (Ach)

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12
Q

Released by preganglionic neuron onto postganglionic for both systems

A

Acetylcholine (Ach)

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13
Q

Receptor on postganglionic cells for both systems

A

Nicotinic receptors

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14
Q

What is always excitatory to post-ganglionic cells?

A

Acetylcholine

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15
Q

System with 1st neuron short, 2nd long

A

Sympathetic

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16
Q

System with 1st neuron long, 2nd short

A

Parasympathetic

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17
Q

What hormones augment sympathetic nervous system?

A

Norepinephrine and epinephrine

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18
Q

What do adrenergic receptors bind?

A

Norepinephrine and epinephrine

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19
Q

Adrenergic receptor that is on most sympathetic targets, excitatory, and binds NE>Epi

20
Q

Adrenergic receptor that is excitatory, and binds NE=Epi, raises heartrate by force of contraction

21
Q

Adrenergic receptor that is inhibitory, relaxes smooth muscle, binds Epi»>NE

22
Q

Molecule that binds a receptor

23
Q

Ligand made by body

24
Q

Ligand as a drug, not made by body

25
Types of Exogenous ligands
agonists and antagonists
26
Exogenous ligand that mimics action of endogenous ligand
Agonist
27
Exogenous ligand that binds but prevents cellular action (Blocker), prevents action of endogenous ligands
Antagonists
28
Manages hypertension by lowering heartrate and force of contraction
B1 Antagonist
29
B1 Antagonist medication
Atenolol, metropolol
30
B2 Agonist medication
Albuterol, salmeterol
31
Helps with Asthma
B2 Agonist
32
System that controls skeletal muscle
Somatic
33
Motor unit
Single motor neuron and muscle fibers it stimulates
34
Motor endplate potential
graded depolarization
35
Cells that generate repeatable action potentials
Excitable cells
36
Prevents Ach buildup in motor endplate
Ach Esterase
37
Causes massive release of Ach from motor nerves with no AP's
Toxin from spiders
38
Toxin from spiders causes
Involuntary muscle contraction
39
Prevents Ach release from motor neurons
Botulinum toxin (botox)
40
Botulinum toxin (botox)
muscles to lose control
41
Where does Curare come from
produced by dart frogs
42
alkaloid blocker that binds Ach receptors but doesn't allow activation
Curare
43
Used to paralyze diaphragm in NICU for ventalators
Curare
44
Inactivate Ach esterase
Nerve gasses
45
Causes muscle rigor and suffocation
Nerve gasses
46
Autoimmune disease where antibodies fight Ach receptors, block them
Myasthenia Gravis
47
Products of immune B cells, large proteins
Antibodies