Chondroitin Sulphate

Question 1

What is Chondroitin Sulphate?

Answer 1

Chondroitin sulphate is a type of glycosaminoglycan (GAG) and a major component of the extracellular matrix in connective tissues, especially in cartilage and joint connective tissue. It provides resistance to compression, partially by thickening synovial fluid.

Question 2

What are the therapeutic uses of Chondroitin Sulphate?

Answer 2

Chondroitin sulphate is used for osteoarthritis. It protects cartilage by reducing degradative enzymes, decreasing inflammation (COX-2, CRP), and increasing hyaluronic acid synthesis for joint lubrication.

Question 3

What is the recommended dosage for Chondroitin Sulphate in osteoarthritis?

Answer 3

200–400 mg two to three times a day or 1000–1200 mg as a single daily dose.

Question 4

What are the absorption rates of Chondroitin Sulphate?

Answer 4

Only 8–18% of orally administered chondroitin is absorbed.

Question 5

What are the safety concerns of Chondroitin Sulphate supplementation?

Answer 5

Chondroitin may exacerbate asthma in sensitive individuals and can increase the anticoagulant effect of warfarin, raising the risk of bleeding and bruising.