Dimethyl Glycine

Question 1

What is Dimethyl Glycine (DMG)?

Answer 1

DMG is trimethyl glycine (betaine) after it has donated one methyl group during the methylation of homocysteine and only exists for seconds at a time.

Question 2

What is the main therapeutic use of Dimethyl Glycine (DMG)?

Answer 2

DMG is primarily used in the treatment of autism, improving behavior, eye contact, frustration tolerance, speech, and reducing seizures.

Question 3

What is the typical starting dosage of DMG for preschool-aged children?

Answer 3

65 mg daily with breakfast for preschool-aged children.

Question 4

What is the recommended dosage range for older children and adults taking DMG?

Answer 4

Older children: 125 mg daily. Adults: 250–1000 mg daily, gradually increasing the dose to 500 mg for children and up to 1000 mg for adults.

Question 5

What should be done if an increase in hyperactivity occurs when taking DMG?

Answer 5

If hyperactivity increases, the dosage should be decreased.

Question 6

How does DMG compare to TMG for autistic patients?

Answer 6

DMG is better tolerated than TMG for autistic patients.