Clinical features of COPD Flashcards Preview

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Flashcards in Clinical features of COPD Deck (12):
1

COPD is characterised by what?

Airflow obstruction that does not change markedly over several months

2

Name 3 diseases associated with airflow obstruction

Chronic bronchitis
Emphysema
Asthma

3

Why is it that those with a lower socio-economic status are more likely to have COPD?

Due to a higher prevalence of smoking and a worse diet

4

What percentage of COPD is attributable to smoking?

85%

5

What is the function of alpha-1-antitrypsin?

It neutralises enzymes released by neutrophils

6

Where is alpha-1-antitrypsin produced?

The liver

7

What is a pack year?

A pack year equals having 1 pack of cigarettes (20 cigarettes) every day for a full year

8

What is the rate of decline of FEV1 for a non-smoker?

Around 30ml/year

9

Maternal smoking causes the child to have what at age 25?

An FEV1 of 75% of what it should be

10

What is the main differentiation between COPD and asthma?

COPD will worsen, as with asthma it will alternate, on some days it will be better than others

11

What response will a person with COPD have to a short-term dose of oral corticosteroids?

Minimal response

12

What will happen to someone with COPD during an infection in terms of their breathlessness?

The breathlessness will increase