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Respiratory Block > Management of Asthma > Flashcards

Flashcards in Management of Asthma Deck (32):
1

What is asthma described as?

Respiratory disorder where there is narrowing of the airways

2

As well as a host factor, what else is required for asthma to be present?

An external irritant

3

What is the smooth muscle narrowing due to?

Histamine release

4

What percentage of hospital admissions for asthma are avoidable?

75%

5

How is asthma mainly diagnosed?

Clinically

6

What is the function of the inhaler?

To try and blunt the response of external irritants

7

What does pMDI stand for?

Pressured metered dose inhalers

8

What percentage of the drug in an inhaler actually gets to the lung?

10-20%

9

What is the drug kept as in a dry powder inhalers?

A sugar coated particle

10

What is the treatment for step 1 in asthma treatment?

Short acting Beta-2 agonists

11

In step 2 of asthma treatment, what would you give to help the patient?

Regular treatment of steroid inhalers

12

What are the 3 main advantages of ICS?

Low dose
Delivered to the site of action
Minimal side effects

13

In step 3, what is added to treatment for asthma?

An inhaled long-acting B2 agonist

14

What is the main advantage of formoterol compared to other long acting B2 agonists?

It has a quicker onset of action

15

In what step are LTRAs first introduced for asthma treatment?

Step 4 - alongside inhaled steroids

16

What are the main problems with theophylline?

It has a narrow therapeutic index
Unpredictable metabolism

17

What is omalizumab?

A monoclonal antibody against IgE

18

What does SANE stand for?

Short acting beta agonist/week
Absence from school/nursery
Nocturnal symptoms/ week
Excertional symptoms/week

19

Which three age ranges are there for the stepwise approach to treatment?

Adults
5-12 year olds
Under 5's

20

Even if severe asthma, what should be the first course of treatment?

ICS

21

What is the best way to give corticosteroids

Through inhalers

22

During step 1 of asthma treatment for children, when should ICS only be taken?

When needed to relieve symptoms

23

When should step 2 of asthma treatment be given?

When inhaled B2 agonists are being used 3 times a week or more
OR
When symptomatic 3 times a week or more

24

What is the main suggestion for step 3 treatment for child asthma?

A long-acting B-agonist

25

What is the main side effect of ICS?

1/2 - 1 cm reduction in height

26

When is the increase of positive effects of ICS most prevalent?

When you go from low to medium dose of ICS

27

What can help prevent the chance of getting oral candidiasis as a side effect of ICS?

Brushing teeth after taking inhaler

28

Long acting beta agonists have to be used alongside what?

ICS

29

What are the main issues that contribute to asthma treatment not working?

Wrong diagnosis
Psychological issues
Compliance issues

30

What is the % lung deposition of ICS for the actual drug without a spacer?

31

How can you double the effectiveness of an inhaler?

Shaking it inbetween uses

32

What percentage of lung deposition do dry powder devices achieve?

20%