Flashcards in Coronary Artery Disease Newman Deck (14):
Chronic stable Angina is
dyspnea and chest tightness on exertion. Comes from an imbalance in O2 supply and demand
Acute Coronary Syndrome
Often described as feeling like an elephant on your chest. Involves plaque in an artery rupturing and clogging a coronary artery.
Substances like thromboxane A2 and endothelin are released.
WHat are the two determinants of myocardial oxygen demand
Systolic Blood Pressure and Heart Rate....along with contractile force and ventricular dimensions. Newman only wants the first two
The degree of stenosis in coronary artery disease is significant at 70%
What does the treadmill test do?
Increases heart rate and systolic blood pressure so that you can see how the heart responds to increased demand for O2
ST elevation Myocardial Infarction...total occlusion of a coronary artery.
What constitutes ANgina
Usually more than 5 minutes never more than 30...more than 30 is not heart pain
Associated with increased sympathetic activity and pale color
Causes of arrhythmias
hypoxia, hypokalemia, increased CO2, Acidosis, Drugs like Digoxin
When one breathes in, Heart rate decreases. This is exacerbated in Cardiac Tamponade
In cardiac tamponade, left ventricular volume decreases because the pressure around the heart won't allow the right atrium to passively fill. This leads to a decrease in preload thus cardiac output, thus Blood Pressure.
True...Pulsus paradoxus leads to a lowering of blood pressure due to this.
Pulmonary artery catheter used to measure
Ejection fraction =
Stroke volume over end diastolic volume