Day 6 Flashcards

1
Q

does size of peptide impact importance

A

no

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2
Q

contain permanently associated chemical components

A

conjugated proteins

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3
Q

non amino acid part of conjugated protein

A

prosthetic group

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4
Q

proteins containing lipids

A

lipoproteins

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5
Q

proteins containing sugars

A

glycoproteins

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6
Q

proteins containing specific metals

A

metalloproteins

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7
Q

covalent bonds linking amino acid residues in a polypeptide chain

A

primary structure

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8
Q

recurring structural patterns

A

secondary structure

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9
Q

3D folding of polypeptide

A

tertiary structure

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10
Q

2+ polypeptide subunits

A

quaternary structure

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11
Q

describes spatial arrangement of the main chain atoms in a segment of a polypeptide chain

A

secondary structure

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12
Q

common types of secondary structure

A

alpha helix, beta conformation, beta turn, random coils

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13
Q

how many atoms of the peptide group lie in a single plane

A

6

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14
Q

what prevents rotation

A

partial double bond character of c-n peptide bond

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15
Q

simplist arrangement, max number of hydrogen bonds

A

alpha helix

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16
Q

backbone wound around an imaginary longitudinal axis

A

alpha helix

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17
Q

r groups protrude in or out of the backbone in an alpha helix

18
Q

r groups protruding away from helical backbone

A

right handedness

19
Q

most common handedness of alpha helix

A

right handed

20
Q

less stable, not observed in proteins

A

left handedness

21
Q

gives significant stability in amino terminus

A

intrahelical hydrogen bonds

22
Q

what affects the stability of alpha helix

A

amino acid sequene

23
Q

what can destabilize the alpha helix

A

charge, size, and shape of r groups

24
Q

what can stabilize alpha helix

A

formation of ion pairs and hydrophobic effect

25
small electric dipoles in each peptide bond align thru what
hydrogen bonds
26
negatively charged amino acids often found where
near the NH3+ terminus
27
positively charged amino acids often found near where
near the COO- terminus
28
introduces destabilizing kink in helix
proline
29
what part of proline is part of rigid rign
nitrogen
30
high conformational flexibility, take up coiled strucutes
glycine
31
backbone extends into a zigzag, what conformation
beta conformation
32
single protein segment
beta strand
33
several stands in beta conformation side by side
beta sheet
34
adjacent polypeptide chains in a beta sheet can be what
antiparallel or parallel
35
opposite orientation
antiparallel
36
which occurs more freq, parallel or anitparallel
antiparallel
37
same orientation
parallel
38
connect ends of two adjacent segments of an antiparallel beta sheet
beta turn
39
how many residues involved in beta turn
4
40
hydrogen bond forms between what in a beta turn
first and fourth residue
41
which two amino acids ovten occur in beta turns
glycine and proline