DNA methylation mediated gene silencing Flashcards Preview

Biochemistry 431 > DNA methylation mediated gene silencing > Flashcards

Flashcards in DNA methylation mediated gene silencing Deck (2)
1

Process

1) MeCp2 binds to methylated DNA
(CPG islands) 2) MeCp2 recruits sin3A (histone deacetylase) 3) leads to silencing

2

Sin3A

histone deacetylase

Decks in Biochemistry 431 Class (80):