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Flashcards in Sensitivity Adjustments Deck (2)
1

How do cells adjust their sensitivity to a signal?

1) The receptor can be endocytosed or 2) the receptor could be dephosphorylated

2

How is the b-adrenergic receptor degraded?

Bark binds to ser residues on carboxyl terminus of receptor following GsBy dissociation causing phosphorylation; Barr binds to phosphorylated ser residues on carboxyl terminus of the receptor; receptor-arrestin complex enters the cell by endocytosis;

Decks in Biochemistry 431 Class (80):