Sensitivity Adjustments Flashcards Preview

Biochemistry 431 > Sensitivity Adjustments > Flashcards

Flashcards in Sensitivity Adjustments Deck (2)

How do cells adjust their sensitivity to a signal?

1) The receptor can be endocytosed or 2) the receptor could be dephosphorylated


How is the b-adrenergic receptor degraded?

Bark binds to ser residues on carboxyl terminus of receptor following GsBy dissociation causing phosphorylation; Barr binds to phosphorylated ser residues on carboxyl terminus of the receptor; receptor-arrestin complex enters the cell by endocytosis;

Decks in Biochemistry 431 Class (80):