Targeting to the ER SRP Flashcards Preview

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Flashcards in Targeting to the ER SRP Deck (3)
1

SRP

Signal Recognition Particle

2

What is the purpose of the SRP?

To target peptides the ER

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SRP function process

1) SRP binds to N-terminus of the polypeptide and ribosome by sitting in the A site halting translation 2) Binding help peptide to find SRP receptor on the ER 3) protein enters ER unfolded 4) signal peptidases cleave signal sequence.

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