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Flashcards in Endorine D/O PPt- Josh Deck (91)
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1

Endocrine System:

5 general fxns

 

  1. Reproduction & CNS development in Fetus
  2. Growth and Development
  3. Reproductive system Coordination
  4. homeostsis of body
  5. adaptive responses when homeostsis is threatened

 

2

Endocrine System:

is a group of glands throughout the body , that synthesize chemical messengers called what?

Hormones

3

Endocrine System:

name 10 glands

  1. Pineal gland
  2. Hypothalamus
  3. Pituitary
  4. Thyroid
  5. Parathyroid
  6. Thymus
  7. Adrenal glands
  8. Pancrease
  9. Ovary
  10. Testis

4

Endocrine System: what Hormomes are released? And what is the function?

Hypothalamus

  • gonadatropin-releasing hormone (GnRH)
  • Oxytocin & ADH formation
  1. hemostasis

5

Endocrine System: what Hormomes are released? And what is the function?

Pineal

  • Melatonin
  • Seratonin
  1. basic needs/ Body Clock

6

Endocrine System: what Hormomes are released? And what is the function?

Pituitary Ant (adenohypophysis)

 

  • TSH
  1. thyroid activity
  • ACTH
  1. Adrenal cortex activity, fats, gylcogen, stress resistance
  • Somatropin
  1. bone growth; fat & sugar levels
  • FSH
  1. Ova & sperm maturation
  • Luteinising (LH)
  1. Corpus Lutem formation; Lactation
  • Interstitial Cell Stimulating (ICSH)
  1. Secretion of testosterone
  • Prolactin
  1. Lactation

7

Endocrine System: what Hormomes are released? And what is the function?

Posterior pituitary

(neurohypophysis)

  • Oxytocin
  1. uterine muscles
  • ADH
  1. Kidney fxn; prevent H2O loss

8

Endocrine System: what Hormomes are released? And what is the function?

thyroid

  • Thyroxine (T4)
  • Tri-iodothyronine (T3)
  1. cellular metabolism
  2. protein breakdown
  3. glucose uptake

9

Endocrine System: what Hormomes are released? And what is the function?

Parathyroid

  • Parathormone
  1. Ca++ balance & utilization
  2. functioning on nervous system

10

Endocrine System: what Hormomes are released? And what is the function?

Thymus

  • Thymosin (blood)
  • Thymopoetine (protein)
  1. Immunity
  2. Neuromuscular activity

11

Endocrine System: what Hormomes are released? And what is the function?

Pancreas

  • Glucagon
  1. rises blood sugar levels
  2. releases glucose into blood
  • Insulin
  1. Lowers blood sugar
  2. converts glucose for uptake

12

Endocrine System: what Hormomes are released? And what is the function?

ovaries

  • Oestrogens
  1. primary & secondary sexual maturity
  • Progesterone
  1. Menstrual flow
  2. fetal development

13

Endocrine System: what Hormomes are released? And what is the function?

testes

  • Tesosterone
  1. Male primary & secondary sexual maturity

14

Endocrine System: what Hormomes are released? And what is the function?

Adrenal cortex

  • Aldosterone
  1. MINERALOCORTICOID regulating Na+ 
  2. K+ Balance
  3. Water regulation
  • Cortisone
  • Cortisol
  • Corticosterone
  1. GLUCOCORTICOIDS maintaining fuel reserve/ reaction to stress/ antiflammatory & tissue repair
  • Androgens & Oestrogens
  1. Reproductive organ fxn
  2. secondary sexual characteristics

15

Endocrine System: what Hormomes are released? And what is the function?

Adrenal medulla

  • Adrenaline (80%)
  • Noradrenaline (20%)
  1. fight or floght

16

Mechanisms of Hormonal Communication:

what are the 3 ways hormones communicate

  • AUTOcrine
  • PARAcrine
  • ENDOcrine

17

Mechanisms of Hormonal Communication:

AUTOcrine?

within cell

18

Mechanisms of Hormonal Communication:

PARAcrine

B/t local cells ( aka just pancreas)

19

Mechanisms of Hormonal Communication:

ENDOcrine

B/t remote cells (AKA ADH and collecting duct of kidney)

20

Regulation of Hormone Release:

what are the 3 mechanisms for regulation of hormone release?

 

  1. Chemical factors (Blood sugar or Ca++ levels)
  2. Endocrine Factors ( hormone from one gland stimulating another)
  3. Neural control

21

what is teh most common type of feedback system in the endocrine system

negative feedback

22

what the fuck is the HPA- axis?

the  Hypothalmic-Pituitary-Adrenal axis

23

Hypothalmic-Pituitary-Adrenal axis (HPA)

what do they release

 

  • Hypothalamus releases CRH to stimulate
  • Anterior pituitary to release ACTH to stimulate
  • adrenal cortex to release CORT (and epi and Norepi)

cool thing is the CORT has a negative feedback loop to re stimulate the hypothalamus

 

24

Hypothalmic-Pituitary-Adrenal axis (HPA)

when does this even kick in?

Stress baby stress

25

Hormone receptors:

what are the 2 different ways the hormones are soluble

  • water
  • lipid

26

Hormone receptors:

what form is usuall free (unbound) in plasma

water soluble

27

Hormone receptors:

what form is usually bound to protein

lipid soluble

28

Hormone receptors:

only what form of hormones can signal a target cell

free

29

Hormone receptors:

water soluble hormones bind w/ receptors where?

In or on the cell membrane

30

Hormone receptors:

steroid hormones are lipid soluble and bind how

diffuse across cell membrane