Test #2 Lupus ARTICLES - Rude man Flashcards Preview

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Flashcards in Test #2 Lupus ARTICLES - Rude man Deck (8)
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1

What is systemic lupus erythematosus?

a chronic inflammatory disease of unknown cause that can affect the skin, joints, kidneys, lungs, nervous system, serous membranes and/or other organs of the body.

immunologic abnormalities, especially the production of a number of antinuclear antibodies, are another prominent feature of the disease.

2

Which gender is affected more frequently?

women, especially in their 20s and 30s

3

What are the three most common symptoms that occur during the course of the disease?

fatigue, fever, and weight loss

(these occur in 50 - 100 percent of patients)

4

Arthritis occurs in what percentage of patients at some time during their illness?

> 90%

5

What is the most common skin lesion that occurs with lupus?

the butterfly rash (erythema over the cheeks and nose)

6

Pleuritic chest pain occurs in approx. ____ % of patients with lupus.

approx. 50 %

7

What are some of the presenting clinical manifestations for lupus? (there are 11 noted from the article)

-unexplained fever, fatigue, and weight loss
-photosensitive rash
-arthritis
-raynaud phenomenon
-serositis (pleuritis, pericarditis, peritonitis)
-nephritis or nephrotic syndrome
-neurologic symptoms, such as seizures, psychosis or stroke
-alopecia
-phlebitis
-recurrent miscarriage
-anemia

8

Which antibody test is the best diagnostic test for lupus and should be performed whenever lupus is suspected?

the antinuclear antibody (ANA) test

(a positive titer is usually 1:160 or higher)