Test #2 Lupus ARTICLES - Rude man Flashcards Preview

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Flashcards in Test #2 Lupus ARTICLES - Rude man Deck (8)
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What is systemic lupus erythematosus?

a chronic inflammatory disease of unknown cause that can affect the skin, joints, kidneys, lungs, nervous system, serous membranes and/or other organs of the body.

immunologic abnormalities, especially the production of a number of antinuclear antibodies, are another prominent feature of the disease.


Which gender is affected more frequently?

women, especially in their 20s and 30s


What are the three most common symptoms that occur during the course of the disease?

fatigue, fever, and weight loss

(these occur in 50 - 100 percent of patients)


Arthritis occurs in what percentage of patients at some time during their illness?

> 90%


What is the most common skin lesion that occurs with lupus?

the butterfly rash (erythema over the cheeks and nose)


Pleuritic chest pain occurs in approx. ____ % of patients with lupus.

approx. 50 %


What are some of the presenting clinical manifestations for lupus? (there are 11 noted from the article)

-unexplained fever, fatigue, and weight loss
-photosensitive rash
-raynaud phenomenon
-serositis (pleuritis, pericarditis, peritonitis)
-nephritis or nephrotic syndrome
-neurologic symptoms, such as seizures, psychosis or stroke
-recurrent miscarriage


Which antibody test is the best diagnostic test for lupus and should be performed whenever lupus is suspected?

the antinuclear antibody (ANA) test

(a positive titer is usually 1:160 or higher)