Flashcards in Test #2 Autoimmune ARTICLES- Dwayne Deck (27):
The majority of carcinoid tumors are located where/
GI tract (appendix, rectum, and ileum)
Slow growing, small bowel tumors
Which tumor bypass the liver
Bone, hepatic, gonadal, pulmonary
S/S of carcinoid tumors
hypotension, HTN, Flushing (most reported), broncho-constriction, diarrhea
carcinoid tumors produce excess of what?
Serotonin (the most) histamine and kinins
Serotonin can cause HTN and Hypotension why?
Indirect stimulation of Norepi release
Serotonin is metabolized by?
MOA and aldehyde dehydrogenase
Most common test to diagnose carcinoid tumors is
5-HIAA 24 hr urine assay
Treatment for carcinoid tumors is
octreotide and surgical removal
synthetic somatostatin with a long 1/2 life
What NMB is recommended for these Pts
Vec r/t cardiovascular stability
Most common complication during surgery?
carcinoid tumors cardiovascular effects what side of the heart
Avoid what drugs R/T histamine release in these pts?
morphine and actracurium
SLE is what? systemic Lupus Erythemiatosus
chronic inflammatory disease of unknown cause that effects jpints, kidneys, lungs, nervous system and serous membranes
2 antibodies common for SLE
anti-double-stranded DNA antibodies and anti-Sm antibodies
what test is the best diagnostic test for SLE
(ANA) antinuclear antibody test
Weight gain in SLE is due to
Hypoalbuminemia, water and salt retention
earliest S/S of Lupus is?
joint pain in 90% of Pt's
Most common lesion in Lupus is?
Butterfly rash over face
Neck and airway assessment crucial, for subluxation of the atlanto-axial joint 25%
joint pain w nodules, worse in the morning but improving with activity, fatigue, wt loss, depression and disability 25% of RA Pts
80% anterior, 5% posterior, Vertical 10-20%
Cricoarytnoid joints, w nodules may distort anatomy, ROM of Neck and TMJ mobility may interfere w mouth opening
All RA Pts should have what test
C Spine xray
Most common symptom of atlanto-axial subluxation is
pain radiating to the occiput the paraesthesia to the shoulders and arms with head movement