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Flashcards in Diabetes PPt-josh Deck (65)
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1

Diabetes:

DM is a disease process that is a resut of what 2 things?

 

  1. Inadequate supply of insulin
  2. inadequate tissue response to insulin

 

2

Diabetes:

what are the 2 types?

  • Type I
  • Type II

IDDM and NIDDM are no onger terms reccommended for use

3

Insulin:

is synthesized by what cells?

Beta cells

4

Insulin:

is regulated by what 3 ways

  1. Chemical
  2. Hormonal
  3. Neural

5

Insulin:

facilitates the uptake of what"?

Glucose

6

Insulin:

is metabolized by what organs

Liver and kidneys

7

Type I DM:

represents what % of cases?

5-10%

8

Type I DM:

___ cells mediated autoimmune destruction of beta cells within the pancreatic islets!

T-cells

9

Type I DM:

what is teh exact cause?

Unk

10

Type I DM:

what is up with the insulin?

there is minimal to complete absence of circulating Insulin

11

Type II DM:

makes up what % of cases

90%

12

Type II DM:

what is up with the insulin

Slow insensitivity and resistance to insulin

13

Type II DM:

there is a slow exhaustion of what cells?

Beta

14

Type I vs Type II:

onset sudden?

1

15

Type I vs Type II:

onset gradual

II

16

Type I vs Type II:

onset mostly adulthood

II

17

Type I vs Type II:

onset any age (mostly young)

 

I

 

18

Type I vs Type II:

THIN bodies

I

19

Type I vs Type II:

chuncky monkies

II

20

Type I vs Type II:

Ketoacidosis

I-often

II-rare

21

Type I vs Type II:

has autobodies

I

22

Type I vs Type II:

endogenous insulin low or absent

I

23

Type I vs Type II:

endogenous insulin normal, decreased, or increased

II

24

DM:

cllinical features!

  • Polydipsia
  • Polyuria
  • Polyphagia
  • Tired
  • Fungal infection
  • poor wound healing
  • Deterioration of vision

25

DM:

complications

  • DKA
  • HHS
  • Microvasular
  • Macrovascular
  • Autonomic neuopathy

26

DM:

what are the 3 main microvascular comlications

  1. Nephropathy
  2. Neuropathy
  3. Retinopathy

27

DKA:

most common in what DM

Type I

28

DKA:

the glucose levels exceed what

Renal excretion

29

DKA:

what happens to fluids in the body

Diuresis

Hypovolemia

30

DKA:

give me quick patho

  • Glucose levels exceed renal tubular excretion
  • Diuresis and hypovolemia ensue
  • Increased ketoacidosis
  • Substantial deficits of water K+ Na+ and Phosphorus