Renal Review PPT-josh Flashcards Preview

BioScience II > Renal Review PPT-josh > Flashcards

Flashcards in Renal Review PPT-josh Deck (80)
Loading flashcards...
1


there are 2 kidneys with how many regions?


2

2


What are the 2 regions?


Cortex

Medulla

3


what is the functional unit of the kidney?


Nephron

4


What are 3 improtant functions of the nephron?


Hold filtrate

Excrete end products of metabolism

Absorb Important sunstances

5

The kidney gets what % of CO?


20-25%

6


how many mLs of blood does the kidney receive?


1100-1200 mL

7


what part of the kidney receives the most blood?


Cortex

8


The renal artery divides at the __1__, into several lobar arteries, they run b/t the __2__ of the medulla and turn into the __3__ then into __4__ and to the __5__.

 

  1. hilus
  2. pyramids
  3. interlobular arteries
  4. afferent arterioles
  5. glomerulus

9


Unfiiltered blood exits the kidney via what, to the venous system?


efferent arteriole

10


filtered blood goes where?


back to the body

11


waste is excreted from the kidneys as what?


urine

12


renal blood flow if determined by the ________ ______ ______ across the vascular bed


arteriovenous pressure difference

13


what is the formula to calculate renal blood flow?


Renal blood flow = (MAP - VP) x VR

  • MAP- mean arterial pressure
  • VP- venous pressure
  • VR- vascular resistance

14


Renal blood flow is regulated by what 2 ways?


intrinsic autoregulation

Neural regulation

15


Autoregulation of the kidneys is with a MAP of what?


75-160mmHg

16


w/ neural regulation afferent and efferent arterioles are inervated by the SNS, stimulation of which is associated w/ what? and thus should be avoided


vasoconstriction

17


4 main functions of the kidney?

 

  • maintenance of ECF composition
  • Maintenance of ECF volume
  • Endocrine functions
  • Regulation of Arterial BP

18


Fx of the Kidneys:

what is maintained in the maintenance of ECF composition?

 

  • Ionic composition (electrolytes)
  • Osmolality (Na+ comcentration
  • Conservation of non-ionic components (glucose, amino acids, proteins, water, vitamins)
  • Excretion of products of metabolism (urea, creatine, lactic acid, uric acid)

19



Fx of the Kidneys:

how does the kidney perform maintenance of ECF volume


regulation of Na+ and h2o excretion

20



Fx of the Kidneys:

what endocrine fx does the kidneys perform?

 

  • erythropoietin
  • RAAS
  • Vit D

21


What are the main structures of teh nephron? do it in order as if you were fluid going through it!

 

  • arteriole from renal artery
  • Bowman's capsule
  • Glomerulus
  • Proximal tubule
  • Loop of henle
  • Distal tubule
  • Collecting ducts

22


What structures are in teh Cortex and what structures are in the Medulla?

 

  • Cortex
    • Renal corpuscle (bowmans capsule)
    • proximal tubule
    • Distal tubule
  • Medulla
    • Loop of henle
    • Collecting duct

23

What are the 3 steps of Urine formation and excretion


Glomerular filtration

Tubular reabsorption

Tubular secretion

24


Glomerular Filtration:

GFR get what % of RBF?


20% (125mL/min)

25


Glomerular Filtration:

the GFR is regulated by what?


Juxtaglomerular complex

26



Glomerular Filtration:

What 3 things can increase GFR?

 

  • Increased RBF
  • Dilation of Afferent arteriole
  • Increased resistance inefferent arteriole

27



Glomerular Filtration:

what 2 things can decrease GFR?

 

  • afferent arteriole constriction
  • Efferent arteriole dilation

28


What reabsorbs the bulk of the glomerlar filtrate?


Proximal tubule

29

what iare the  main function of the Loop of henle?

 

  • establishes and maintains an osmotic gradient in the medulla of the kidney
  • regulation of water balance
  • Concentration/dilution of urine

30


The descending loop is highly permeable to ________ but impermeable to ______


Water

Solutes