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Flashcards in Epithelium and Glands Deck (31):
1

Where are three places you can find epithelia

1. external surfaces
2. luminal surfaces: GI tract, respiratory tract, endothelium in blood vessels
3. glands:

2

What are 4 major characteristic of epithelia

1. No (little) ECM
2. free apical surface
3. Avascular (diffusion)
4. Has basal lamina

3

What are types of epithelium

-Simple; 1 layer
- Stratified: 2 layers
1. Squamous: flat
2. cuboidal: cubed
3. columnar: taller

4

Endothelium and mesothelium are ___ ____epithelium

simple squamous- lines blood vessels; all serous membranes- lines body cavities ; peritonuem etc

5

Simple ____

cuboidal; line ducts

6

Skin is ____squamous

stratified; great barrier for protection

7

Psudo _____columnar is found along:

stratified; trachea and bronchi; not everything goes to surface

8

_____epithelium is generally for:

urinary tract; changes depending on how it is stretched.

9

Shape is always based on ____cell not basal

luminal surface

10

Eosin stains ____

dark; collagen fibers

11

Stratified squamous lines:

esophagus, anal canal, distal vagina and urethra

12

If every single cell is reaching the BM then it is a ____stratified epithelium

psuedo; tends to be found along airways, so there will be cilia on apical surface

13

Microvilli inc ___area

surface; specialization for absorption

14

What are stereocilia

just extra long microvilli; not cilia

15

What are cilia

much longer than microvilli; more than just a dark line. Can see microtubules

16

What is the difference between looking at microvilli and cilia

1. In cilia in EM you can see cytoskeletal components inside
2. Much longer; it looks more hairy instead of a dark line

17

Cilia has microtubules that consist of _____ and a basal body that consists of ____

axoneme; centrioles (9 triplets and no central microtubule)

18

Flagella are in ____and cillia are found in _____tract

sperm; respiratory; anything that helps make it move.

19

What are lateral surface junctional complexes

1. Occluding (tight junctions): near apical border; interactions between proteins bet proteins of adjacent cells. form in complexes that form lines.
2. Desmosomes (Adherens):
3. Gap junction: communicating, that creates a pore that allows small molecules and signaling molecules to travel through. Occur in clusters.

20

WHat is Pemphigus

autoimmune disease that attacks desmosomes

21

What does basal lamina refer to

Seen by EM, refers to lamina rara (lamina lucida) and lamina densa
-Produced by epithelial cells
-Reticular fibers formed by CT

22

What does basement membrane include

includes basal lamina and reticular fibers

23

What anchor cell?

1. Focal adhesions; Interact with actin cytoskeletons
2. Hemidesmosomes: interact with intermediate filaments
-They both use INTEGRIN transmembrane proteins

24

Which junctions connect cell-cell and use cadherin protein

1. Zonula adherens-use actin
2. Desmosomes- intermediate filaments

25

What are glands

Specialized epithelium for secretion.

26

What are the types of glands

1. Exocrine: Secrete into lumen, ducts, or surfaces
2. Endocrine: glands secrete into bloodstream
3. Paracrin: glands secrete into interstitium.

27

What are the types of exocrine glands

1. Merocrine: Secretory vesicles containing product fuse with apical membrane; Most sustainable
2. Apocrine: apical membrane buds off with product inside; depletes membrane
3. Holocrine: Product is released when cell undergoes apoptosis

28

Secretory products

Serous secretion: watery, protein rich

Mucous secretion: viscous, carbohydrate rich

29

What is a goblet cell

find along airways and digest tract. secrete mucous that lubricate lining of lumen. Produce a mucous secretion. These are the simplest cells

30

What do you have with a multicellular gland

1. All epithelial derived cells that invaginate in CT that specialize into duct or gland.
2. Name glands based on duct shape.

31

What are the two types of ducts

1. Simple: ducts are unbranched
2. Compound: Ducts are branched
-Can be tubular or alveolar-describe shape