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Flashcards in ETC- Part 1 Deck (19):
1

Inner mitochondrial membrane has ____ which makes it have a large surface area

cristae; very impermeable

2

Outer membrane has ____

porins; permeable

3

NADH enters as complex ___ FADH enters as complex ____

1; 2 (succinate to fumerase)

4

+ charges on the ____of the mitochondrial matrix, whereas - charges are on the inside

outside; inside

5

Electrons get transferred from ___ to ___

lower to higher. (higher are the acceptors)

6

Rotenone inhibits transfer of NADH to

Q and Cyt b

7

Antimycin A inhibits transfer of Cyt B to

Cyt C1

8

CN- or CO inhibit transfer of Cyt a to

oxygen

9

What are the enzyme complexes of the ETC

1. NADH dehydrogenase
2. Succinate dehydrogenase
3. Ubiquinone cytochrome c oxidoreductase
4. Cytochrome oxidase

10

Cytochromes consist of protiens + heme ____ ____and have different classes. They accept 1 electron at a time and absorb visible light differently if oxidized or reduced

prosthetic groups

11

What is the non protein component of ETC

ubiquinone; aromatic ring structure with keto groups that give resonance structures

12

ubiquinone is ____soluble and resides in the ___membrane and can accomodate 1 or ____ e- transfers and also carries proton

fat; inner; 2

13

Complex 1, NADH dehydrogenase processes ___e- at a time and converts the e- from NADH to ____and transfers ___protons

2; QH2; 4

14

Complex 2, Succinate Dehydrogenase is fixed in ___membrane and produces ____It doesnt have any transfer of H+ into intermembrane space

inner; FADH2

15

Complex 3, Cytochrome bc1 processes ____ and transfers e- to ______ and pumps protons into intermembrane space. It is loosely associated and floats in the intermembrane space, thus it is considered a ______ _____. It transfers ____protons as well.

QH2YQ; cytochrome c; "step down transformer"; 4

16

cytochrome C has been identified to have an extra _____. It is important in _____.

job; apoptosis (programmed cell death)

17

what is the process of apoptosis in cytochrome c

1. Permeability transition pore complex opens up
2. cytochrome c moves to cytosol
3. Apaf -1 activates
4. Dimerization of Procapsase -9
5. caspase-9 breaks down proteases of cell
6. cell self destructs from inside out

18

complex 4, cytochrome oxidase, takes e- from cytochrome c to oxygen to produce _____. It pumps protons into _____ and is the source of the majority of the cellular _____stress. It transfers ____ protons.

water; IMS; oxidative; 2

19

Complex V, ATP Synthase, converts ATP + Pi to ____. It is very large. The circular motion of F0 driven by proton gradient like a water wheel.

ATP