Exam 4 - Lec 44 Thyroid Disorders

Question 1

what does the TSH test measure?

Answer 1

pituitary TSH level

Question 2

what does a free T test measure?

Answer 2

direct measurement of free thryoxine

Question 3

what does the ATgA test measure?

Answer 3

antibodies to thyroglobulin

Question 4

what does the TPO-Ab test measure?

Answer 4

thyroperoxidase antibodies

Question 5

what does the TRAb test measure?

Answer 5

thyroid receptor stimulating antibody

Question 6

which test confirms Grave’s disease?

a. TSH
b. Free T4
c. ATgA
d. TPO-Ab
e. TRAb

Answer 6

e. TRAb

Question 7

3 treatment options for hyperthyroidism

Answer 7

-thioamides (propylthiouracil, methimazole)
-radioactive iodine (RAI)
-surgery (thyroidectomy)

Question 8

black box warning for propylthiouracil

Answer 8

hepatic failure

Question 9

20-30 mg propylthiouracil is equivalent to ___ mg of methimazole

Answer 9

1 mg

Question 10

initial dosing for propylthiouracil

Answer 10

50-150 mg TID

Question 11

levothyroxine replacement dosing for uncomplicated (healthy) adult: average starting does ____ mcg/day; increase by ___ - ___ mcg Q__-___weeks

Answer 11

100mcg/day
12.5=25 mcg/day
Q6-8 weeks

Question 12

true or false: thioamides can cause GI upset

Answer 12

true (take with food)

Question 13

agranulocytosis is defined by less than

a. 100/mm3 of neutrophils
b. 500/mm3 of neutrophils
c. 1000/mm3 of neutrophils

Answer 13

b. 500/mm3 of neutrophils

Question 14

true or false: radioactive iodine is not contraindicated in pregnancy, lactation, planning pregnancy <4-6 months

Answer 14

false

(this is absolutely contraindicated)

Question 15

hypothyroidism thyroid supplements (3 of them)

Answer 15

levothyroxine (T4)
liothyronine (T3)
dessicated thyroid -> armour thyroid

Question 16

black box warning for levothyroxine

Answer 16

weight loss