Excretory System Flashcards

1
Q

Passage through excretory system

A

nephron , renal pelvis, ureter, bladder, urethra

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2
Q

Kidney structure

A

cortex, medulla, renal hilum (deep slit in the center of its medial surface, renal artery vein and ureter enter/ exit via the renal hilum)

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3
Q

Portal system

A

2 capillary beds in series for blood to travel through before returning to the heart

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4
Q

Afferent arterioles

A

flow from cortex to the medulla. glomeruli are highly convoluted tufts derived from afferent arterioles

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5
Q

efferent arterioles

A

lead blood away from the afferent form the vasa recta. which isth e secondary capillary bed surrounding the loop of henle

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6
Q

what surrounds the glomerulus

A

bowmans capsule

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7
Q

renal corpuscle

A

bowmans capsule and glomerulus. leads to the pct, descenidng loh, ascending loh, dct, collecting duct

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8
Q

micturition reflex

A

stretching of bladder = parasympathetic nerves fire and detrusor muscle contracts the bladder causins the interal sphinctor to relax

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9
Q

osmoregulation

A

filtration , secretion, reabsorption

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10
Q

filtration

A

hydrostatic pressure in glomerulus is higher than in bowmans space, which causes blood to travel to the nephron. but osmolarity of blood is higher than that in bowmans space, pressure moves against blood into nephron. since hydrostatic pressure is greater than oncotic pressure the blood will move to the nephron

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11
Q

kidney stone

A

buildup of urine behind the stone increases the hydrostatic pressure of bowmans space and therefore filtration is hindered

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12
Q

Filtrate is

A

isotonic to blood

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13
Q

secretion

A

movement of solutes from blood to filtrate anywhere besides bowmans capsule. nephron secretes salts, acids, bases and urea directly into tubule by active or passive transport

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14
Q

reabsorption

A

componds, glucose amino acids and vitamins. movement of solutes from filtrate to blood. what we want to keep

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15
Q

bowmans capsule, pct and dct = primarily focused on

A

identity of particles in urine (keep what body needs, lose what it doesnt)

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16
Q

LOH and collecting duct

A

focused on volume and concentration of urine

17
Q

PCT proximal convoluted tubule

A

reabsorbed= a. a , glucose water soluble vitamins and salts na cl, and water. secreted= H ions, urea , NH3 and K. Dump the “HUNK”

18
Q

descending loop of henle

A

permeable to only water. the deeper you go into the medulla we have increased intertitial conc, so water moves out

19
Q

ascending loop of henle

A

permeable to salts but impermeable to water. so na and cl move out of the filtrate.

20
Q

Diluting segment LOH

A

transition between inner and outer medulla , cells lining are larger, more mitochondria and therefore more active transport. filtrate becomes hypotonic (more dilute) compared to the interstitium in the ascending lOH.

21
Q

countercurrent multiplier system

A

flow of filtrate through LOH is opposite direction from flow of blood through the vasa recta. by making both components flow in opp directions, the filtrate is constantly being exposed to hypertonic blood, which allows for the maximum reabsorp of water

22
Q

DCT - distal convoluted tubule

A

responds to aldosterone, which is a steroid hormone that promotes sodium reabsorption, water follows and this results in concentrated urine and decreased urine volume.

23
Q

Collecting Duct

A

Responsive to ADH and aldosterone. Reabsorbes H20 as permeability of CD increases. Hydrated= means it is impermeable to salt and H20. “point of no return”

24
Q

Mechanism of Aldosterone

A

Basics= aldosterone is a steroid hormone that is secreted by adrenal cortex in response to low bp. How is low bp sensed ? Juxtaglom cells release renin. renin cleaves angiotensinogen to angiotensin I. Angiotensin I gets converted to angiotensin II via ACE. angiotensin II is what promotes the release of aldosterone. Mainly aldosterone alters the ability of DCT and CT to reabsorb sodium. so blood volume increases and bp will then increase. K ion and H ion excreted

25
Q

Mechanism of ADH / Vasopressin

A

Peptide hormone synthesized by hypothal and released by posterior pit in response to increased blood osmolarity. This basically alters the permeability ofo the collecting duct allowing more water to be reabsorbed by making the cell junctions of the duct leaky. extension of this is alcohol and caffiene, which inhibit adh release and therefore can cause frequent excretion of dilute urine

26
Q

What will happen if afferent arteriole constricts

A

bp drops and renin can be secreted to raise bp

27
Q

osmotic pressure

A

sucking pressure that draws water into vasculature by all dissolved particles

28
Q

oncotic pressure

A

osmotic pressure that is attributed to proteins specifically

29
Q

blood osmolarity

A

290-300 mOsm/L

30
Q

Bicarb buffer equation

A

Co2 (g) + H2o (l) H2Co3 (aq) H+ (aq) + HCo3 - (aq)