Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Step2 > FA Haematology > Flashcards

FA Haematology Flashcards

(57 cards)

Start Studying
1
Q

How do platelets bind to vwf

A

GP1b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

PT measures

A

Extrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PTT measures

A

Intrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Warfarin monitor

A

PT (affects both but 7 has shortest half-life)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What synthesizes vit K?

A

Enteric bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How do clotting factors get activated

A

Gamma carboxylation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DOAC reversal

A

Andexanet alfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

tPA can cause

A

Angiooedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Heparin reversal

A

Protamine sulphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dabgatrin reversal

A

Idarucizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Inhibits epoxide reductase

A

Warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Doac vs warfarin metabolism

A

Renal, hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

INR monitoring

A

> 10 - stop and give vit k
4.5 - 10 - hold and can give vit k
<4.5 - hold next dose and then go to maintenance (adjust)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What blood replacement product has high concentration of fibrinogen, VIII, vWF

A

Cryoprecipitate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Who gets haemophilia C?

A

Ashkenazi Jewish

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Best source of factor 8 and fibrinogen?

A

Cryo
FFP also has

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Heyde syndrome

A

Aortic stenosis, GI bleeding, acquired vWD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Diagnosis of vWD

A

Reduced agglitination on Ristocetin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most common inherited bleeding disorder

A

vWD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Treat vWD

A

Desmopressin, antifibrinolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Provoked DVT treatmentt

A

3-6 months
Lifelong if more

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

DVT but anticoagulant is contraindicated

A

IVC filters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Protein C deficiency causes

Study These Flashcards
A

Skin necrosis with warfarin administration

24
Q

APS effects

Study These Flashcards
A

Coagulation defects
Livedo reticularis
Obstetric comp
Thrombocytopenia
SLE

25
Does DIC have haemorrhage or thrombosis?
Both!
26
Antibodies in APS
Lupus anticoagulant Beta 2 glycoprotein Cardiolipin
27
TTP treatment
Plasma exchange, steroids
28
Fibrinogen TTP, HUS, DIC
Only affected in DIC (low)
29
What is wrong on labs in VWD
only increased bleeding (can affect PTT because of factor 8)
30
What is ITP?
IgG against membrane protein G2b/3a
31
Treat ITP
<30,000 or bleeding = steroids, IVIg
32
Haemolytic vs non-haemolytic anaemia
Reticulocyte (increased vs decreased)
33
Microcytic anaemias can be split into
Defect harm (iron def. lead poison, sideroblastic, acd) and global (thalassemia)
34
Non-megaloblastic macrocytic
Liver Alcohol
35
Most accurate IDA test?
Prussian blue bone barrow stain
36
Does thalassemia anaemia respond to iron ?
No
37
Lead lines aka
Burton lines
38
What TB drug can cause sideroblastic anaemia?
Isonizab
39
Microcytic anaemia where serum iron is elevated
Sideroblastic
40
HbH
3
41
Hb Barts
4
42
Warm AIHA
IgG SLE, CLL, penicillin, rifampicin, phenytoin, methyldopa
43
Cold AIHA
IgM Myocoplasma EBV Waldenstrom
44
B12 can be caused by
Diphyllobothrium lactum
45
Phenytoin use causeswhat deficiency
Folate deficiency
46
Felty
Neutropenia Splenomegaly RA
47
ABPA diagnosis
IGE against A fumingatus
48
Leukaemia most accurate test
Bone marrow biopsy with flow cytometry
49
Non-hodgkin vs hodgkin cells
Mainly B Reed Sternberg
50
Alcohol induced lymph node pain
Hodgkins lymphoma
51
Dutcher bodies
Wallenstrom
52
AL amyloid
MM Waldenstrom
53
AA amyloid
RA, inflammatory
54
Transplant between twins
Syngeneic
55
Allogeneic
Donor to genetically different patient
56
GVHD affects
Skin, GI, liver, lung
57

Step2 (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions