FA - Micro - Clinical Bacteriology (2016) Flashcards Preview

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Flashcards in FA - Micro - Clinical Bacteriology (2016) Deck (46):
1

S.epi - Infects ...?

1. Prosthetic devices (eg hip implant, heart valve).
2. IV catheters by producing adherent biofilms.

2

S.saprophyticus - General features:

1. Catalase (+).
2. Coagulase (-).
3. Urease (+).
NOVOBIOCIN RESISTANT.

3

S.sapro is normal flora of ...?

Female genital tract + Perineum.

4

S.pyogenes (GAS) - Pyrrolidonyll arylamidase (PYR)?

POSITIVE.

5

S.agalactiae (GBS) - Pyrrolidonyl arylamidase?

NEGATIVE.

6

S.bovis - Colonize the ...?

GUT.

7

S.gallolyticus?

S.bovis biotype 1.

8

S.gallolyticus - Cause what ...?

BACTEREMIA + SUBACUTE endocarditis.
==> Associated with COLON CANCER.

9

Enterococci - PYR?

POSITIVE.

10

C.tetani - Tx:

1. Anti-toxin +/- vaccine booster.
2. Diazepam (for muscle spasms).
3. Wound debridement.

11

C.botolinum - Local botox injections used to ...?

Treat:
1. Focal dystonia.
2. Achalasia.
3. Muscle spasms.
--> Also used for cosmetic reduction of facial wrinkles.

12

C.perfringens - Spores can survive in ...?

UNDERCOOKED FOOD.

13

C.perfringens - When ingested, bacteria release ...?

Heat-labile enterotoxin --> Food poisoning.

14

C.difficile - For recurrent cases?

1. Consider prior regimen.
2. FIDAXOMICIN.
3. Fecal microbiota transplant.

15

H2S production on TSI agar?

Salmonella + Proteus.

16

H2S production on TSI agar?

Shigella + Yersinia.

17

H.influenza - Culture on ...?

Chocolatee agar --> Contains factors V (NAD+) and X (hematin) for growth.

18

H.influenza - Can also be grown with ...?

S.aureus, which provides factor V through the hemolysis of RBCs.

19

Epiglottitis of H.flu - Endoscopic appearance?

"Cherry-red" in children.

20

Epiglottitis - H.flu - X-RAY?

"Thumbprint sign on x-ray.

21

H.flu - Tx:

1. Amoxicillin +/- clavulanate for mucosal infections.
2. Ceftriaxone for meningitis.
3. Rifampin prophylaxis for close contacts.

22

Salmonella spp. (except S.typhi) - Reservoirs:

Human and animals.

23

Salmonella spp. (except S.typhi) - Spread:

Can disseminate HEMATOGENOUSLY.

24

Salmonella spp. (except S.typhi) - H2S production?

YES.

25

Salmonella spp. (except S.typhi) - Flagella?

YES.

26

Salmonella VS Shigella - Virulence factors:

Salmonella typhi --> Endotoxin; Vi capsule.
Salmonella spp. (except S.typhi) --> Endotoxin.
Shigella --> Endotoxin; Shiga toxin (ENTEROTOXIN).

27

Salmonella spp. (except S.typhi) - ID50?

HIGH.

28

Salmonella spp. (except S.typhi) - Immune response?

PMNs in disseminated disease.

29

Salmonella spp. (except S.typhi) - GI manifestations?

Diarrhea - Possibly bloody.

30

Salmonella VS Shigella - Vaccine?

Salmonella typhi --> ORAL vaccine contains live attenuated S.typhi + IM vaccine contains Vi capsular polysaccharide.
Salmonella spp. (except S.typhi) --> NO VACCINE.
Shigella --> NO VACCINE.

31

Salmonella typhi - Tx:

Ceftriaxone or fluoroquinolone.

32

Salmonella spp. (except S.typhi) - Common sources:

1. Poultry.
2. Eggs.
3. Pets.
4. TURTLES.

33

Salmonella spp. (except S.typhi) - Antibiotics:

NOT INDICATED.

34

Salmonella spp. (except S.typhi) - Gastroenteritis is usually caused by ...?

NON TYPHOIDAL SALMONELLA.

35

Shigella spp. - In order of decreasing order of severity (less toxin produced):

Dysenteriae > Flexneri > Boydii > Sonnei.

36

Lyme - Stage 1:

Early localized ==>
1. Erythema migrans.
2. Flu-like symptoms.

37

Lyme - Stage 2:

Early disseminated ==>
1. Secondary lesions.
2. Carditis.
3. AV block.
4. Facial nerve (Bell) palsy.
5. Migratory myalgias/ transient arthritis.

38

Lyme - Stage 3:

Late disseminated ==>
1. Encephalopathies.
2. Chronic arthritis.

39

What may follow 2o syphilis?

LATENT SYPHILIS --> Positive serology without symptoms.

40

Salmonella spp. (except S.typhi) - Transmission and source:

1. Reptiles.
2. Poultry.

41

Gardnerella vaginalis - A "very special" test ...?

AMINE WHIFF test --> Mixing discharge with 10% KOH ==> ENHANCES FISHY ODOR.

42

Rickettsial diseases and vector-borne illnesses - Rash common:

1. RMSP.
2. Typhus.

43

Rickettsial diseases and vector-borne illnesses - Rash rare:

1. Ehrlichiosis.
2. Anaplasmosis.
3. Q fever.

44

MCC of culture-NEGATIVE endocarditis:

C.burnetii.

45

Chlamydia D-K - Neonatal disease can be acquired during ...?

Passage through INFECTED birth canal.

46

Alpha-hemolytic bacteria - What causes the greenish/brownish color without clearing around growth on blood agar?

PARTIAL REDUCTION OF HEMOGLOBIN.