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Flashcards in Mycoplasma Deck (13):
0

What is the morphology of Mycoplasma pneumoniae?

1. No cell wall
2. Pleomorphic
3. Smallest bacterium capable of groin and reproducing outside a living cell (smaller than some viruses).
4. Motile (glides)

1

What is the metabolism of M.pneumoniae?

1. Requires CHOLESTEROL for membrane formation.
2. Facultative anaerobe.

2

What is the virulence of M.pneumoniae?

Protein P1 - adheres to epithelial cells of the respiratory tract.

3

What can M.pneumoniae cause?

1. Tracheobronchitis
2. Walking pneumonia (atypical pneumonia)

4

How can we diagnose M.pneumoniae?

1. Cold agglutinins
2. Complement fixation test
3. Culture
4. Rapid identification tests

5

How can we culture M.pneumoniae?

1. Requires cholesterol and nucleic acids.
2. Add penicillins to inhibit growth of contaminating bacteria.
3. Dome shaped colonies with "fried-egg" appearance or "mulberry" appearance (in the case of M.pneumoniae).

6

How can we rapidly identify M.pneumoniae?

Sputum can be tested with DNA probes (nucleic acid hybridization). PCR of sputum samples.

7

What is important to keep in mind about M.pneumoniae infection?

1. Chest X-Ray will show patchy infiltrates that look worse than physical exam and clinical suggest.
2. Disease usually occurs in children, adolescents, and young adults.

8

What is the morphology of Ureaplasma urealyticum?

1. No cell wall
2. Pleomorphic

9

What is the metabolism of Ureaplasma urealyticum?

1. Requires cholesterol
2. Urease metabolizes urea into ammonia and CO2.w

10

What can U.urealyticum cause?

Non gonococcal urethritis: burning on urination, with a yellow mucoid discharge from the urethra.

11

How can we diagnose U.urealyticum?

1. Requires cholesterol and urea for growth.
2. Colonies are extremely tiny (T-strain).

12

Do Mycoplasma and Ureaplasma have toxins?

No toxins.