Flashcards in Female incontinence; 4.15 Deck (21):
What kind of androgen receptors are found in the bladder dome?
What is the effect of having beta-receptors in the bladder dome when sympathetics are active?
The bladder relaxes...this is the case while STORING urine
What kind of androgen receptors are found at the bladder neck (internal urinary sphincter)?
What is the effect of having alpha-receptors in the bladder neck when sympathetics are firing?
The sphincter constricts...this would also be necessary while STORING urine
Where else are alpha-receptors in the urinary system?
The urethra...again, sympathetics would cause the urethra to constrict so the bladder won't leak
Besides sympathetic activity, what else is going on during urine storage?
Cholinergics are inhibited
What nerve sends the sympathetic control to the bladder?
What nerve sends the cholinergic activity?
What are some lifestyle modifications that can be made to treat stress incontinence?
What can be done to strengthen the pelvic floor?
Extracorporeal magnetic innervation
What are devices that can be used to occlude the urethra?
What are some meds that can be used to treat stress incontinence, despite not being approved?
Why is estrogen given intravaginally?
Because it would WORSEN the condition if it was given SYSTEMICALLY
What is the problem with duloxetine?
Duloxetine has more side effects
Are alpha-adrenergics commonly used?
No...alpha-adrenergics are not commonly used
What are some non-medicinal treatment options for urge/overactive bladder?
Remove worsening drugs if possible
Pelvic floor strengthening
What are some medicinal treatments for urge/overactive bladder?
When are anticholinergics contraindicated?
Narrow angle glaucoma
Old frail people
What is a risk of using beta-agonists?
Urinary retention (worse with concurrent anticholinergic use)
Besides meds and lifestyle changes, how else can urge/overactive bladder be treated?
Tibial nerve stimulation