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Flashcards in Simple Female Repro Drugs Deck (18):
1

How do you promote folliculogenesis in women with hypothalamic anovulatory function?

FSH and LH with daily injection

2

How do you achieve super ovulation in normal ovulatory women?

FSH/LH on d 2-3 of menstrual cycle

3

What are the urinary derived gonadotropins?

Menotropin and urofolitropin. (gonadoTROPIN and these are TROPINs)

4

What ar ethe recombinant human gonadotropins?

Follitropin a and follitropin b

5

What SERM is an antagonist or the estrogen receptor in the hypothalamus?

Clomiphene Citrate (multiple fetuses are possible)

6

What is the GnRH analog?

Leuprolide can be used in lieu of GnRH. Nonpulsatile will shut down pituitary

7

GnRH Antagonist?

Cetrorelix, Ganirelix (relix will make your testes/ovary relax)

8

SERM that is antagonist in Breast, Vasculature and agonist in uterus, bone, lipoproteins?

Tamoxifen (has a risk of uterine cancer)

9

Pure estrogen antaonist?

Fulvestrant. Used for estrogen receptive breast cancer

10

SERM that is agonist in bone and lipoproteins but antagonist in breast and uterus?

Raloxifene (used in uterine cancer b/c antagonist)

11

SERM that is antagonist in breast and no other known effects?

Toremifene (2remifene as in 2 breasts that are being antagonized)

12

Steriodal aromatase inhibitor? Is it reversible?

Exemestane is steroid, so it is nonreversible

13

Nonsteroidal aromatase inhibitor? Is it reversible?

Anastrozole and letrozole. Nonsteroidal, reversible (end in zole so block steroid synth like azoles do in antifungals)

14

Synthetic progestane?

Medroxyprogestreone acetate

15

Synthetic estrane?

Norethindrone

16

Synthetic gonane?

Levonorgestrel. Potent at low dose

17

Progesterone antagonist for either emergency contraception or terminating early pregnancy?

Mifepristone: emergency contraceptive at small dose or larger dose to terminate early preggers. Use Mif if you screwed up and you don't want her to become a Milf

18

Progesterone antagonist for emergency contraception?

Ulipristal acetate for emergency contraception as it delays ovulation and alters endometreium.