FINAL EXAM: Unit 2 Flashcards
afferent / sensory neurons
take into TO the CNS
efferent / motor neurons
take info FROM the CNS
what do Schwann cells do?
myelination of PNS
what do oligodendrocytes do?
myelination of CNS
what do satellite cells do?
protective layer around cell bodies
what do astrocytes do?
form BBB, NT uptake
what opens mechanically-gated channels?
pressure, stretch
what opens chemically-gated channels?
ligand & receptor
what opens voltage-gated channels?
cell membrane potential (depo, hyper)
which type of potential, graded or action, is excitatory and inhibitory?
graded potential
which type of potential, graded or action, contains only voltage-gated channels for K+ and Na+?
action potential
what happens during the depolarization stage of an action potential?
Na+ entry
-IG open
-AG open
what happens during the repolarization stage of an action potential?
K+ exits
-IG close
-AG open
what is an absolute refractory period?
no stimulus can trigger AP
what is a relative refractory period?
larger than normal stimulus can trigger
how does hyperkalemia impact action potentials?
RMP increases
-a smaller stimulus can trigger AP
how does hypokalemia impact action potentials?
RMP decreases
-need a larger stimulus to trigger AP
what receptors does ACh use? whats the difference b/w them?
nicotinic: ionotropic (receptor/ion), Na+ entry, excitatory
muscarinic: metabotropic (GPCR)
what type of receptor do amines use?
NE, E, dopamine
-metabotropic (alpha, beta)
what type of receptor do amino acids use? describe the effects of each major type of AA
ionotropic
-glutamate: excitatory, Na+ entry
-GABA, glycine: inhibitory, Cl- entry
what type of receptor do purines use?
adenosine, ATP, cAMP
-metabotropic
what type of receptor do gases use?
NO RECEPTOR
what type of receptor do lipids use?
eicosanoids
-metabotropic
what is the pathway of exocytosis to release a NT?
- AP -> depolarization
- Ca2+ entry
- exocytosis of vesicle
- NT release
- goes to postsynaptic receptor