Flashcards in Fungal Meningitis Deck (15):
1
Fungal meningitis is rare except in?
immunocompromised pts
2
How are cases confirmed
- microscopic observation of yeast forms in CSF samples
- Culture CSF for fungi
- Antigen detection for fungi such as : Cryptococcus
3
Treat fungal meningits with
AMPHOTERICIN B often in combo with flucytosine
4
Most common fungal agent in IC pts is
cryptococcus neoformas
5
C. Neoformans found where
pigeon dropings
6
85% of crypto infections occur in who?
HIV pts
7
Where is cryptococcus found
tropical regions, west coast, AUSTRALIA
8
steroid injection fungus
exserohilum rostratum
9
Which cryptococcus is seen most often in healthy individuals
Cryptococcus gatti
10
Cryptococus are ALWAYS ENCAPSULATED
KNOW
The capsule is a polysaccharide, is anti-phagocytic and blocks opsonization
11
Initital crypto infection is what
asymptomatic pulmonary infection
12
Diagnosis of Crypto
yeast with halos in INDIA INK stained CSF of meningitis pts.
13
exsorhilum rostratum
common environmentalblack mold that rarely causes infection
not previously linked to meningitis
14
Treatment of exsorhilum
voriconazole IV for 3 mos or more
severe cases gt ampho B for 3 months or more
15