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Flashcards in Fungal Meningitis Deck (15):
1

Fungal meningitis is rare except in?

immunocompromised pts

2

How are cases confirmed

- microscopic observation of yeast forms in CSF samples
- Culture CSF for fungi
- Antigen detection for fungi such as : Cryptococcus

3

Treat fungal meningits with

AMPHOTERICIN B often in combo with flucytosine

4

Most common fungal agent in IC pts is

cryptococcus neoformas

5

C. Neoformans found where

pigeon dropings

6

85% of crypto infections occur in who?

HIV pts

7

Where is cryptococcus found

tropical regions, west coast, AUSTRALIA

8

steroid injection fungus

exserohilum rostratum

9

Which cryptococcus is seen most often in healthy individuals

Cryptococcus gatti

10

Cryptococus are ALWAYS ENCAPSULATED

KNOW
The capsule is a polysaccharide, is anti-phagocytic and blocks opsonization

11

Initital crypto infection is what

asymptomatic pulmonary infection

12

Diagnosis of Crypto

yeast with halos in INDIA INK stained CSF of meningitis pts.

13

exsorhilum rostratum

common environmentalblack mold that rarely causes infection

not previously linked to meningitis

14

Treatment of exsorhilum

voriconazole IV for 3 mos or more

severe cases gt ampho B for 3 months or more

15

If CSF contains 5 or more WBCs

start voriconazole