Kids Brain Tumors Flashcards Preview

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Flashcards in Kids Brain Tumors Deck (31):
1

Most common pediatric solid tumor

brain tumor

2

Brain tumor peaks

Early childhood and late adulthood

3

INFRATENTORIAL tumors are most common in kids whereas SUPRATENTORIAL tumors are more common in adults

ok....

In the first year of life supratentorial tumors are more common

4

High grade gliomas are .... in peds

Rare

5

Most common childhod tumor

Astrocytoma (pilocytic)

6

Astrocytoma often found where

posterior fosterior

7

Unlike adults and older children, younger children have a relatively high occurence of tumors where

cerebellum and brain stem

8

Neurofibromatosis 1 casues what tumor types

Optic Gliomas
Meningiomas
Ependymomas

9

Neurofibromatosis II causes

Bilateral vestibular schwanomas

10

Tuberous Sclerosis

Subependymal giant cell tumors

11

Von Hippel Lindau

Hemangioblastomas

12

Li Fraumeni syndrome

Multiple brain tumor types but commonly astrocytoma and medulloblastoma

13

clinical manifestations of a supratentorial tumor

localizing findings
seizures
hemiparesis

14

Midline tumor findings

Endocrinopathies (diabetes insipidus, growth disorders, decreased vision, visual field issues)

15

Infratentorial tumors

signs of increased ICP due to compression of the fourth ventricle

16

Brainstem tumors show

cranial nerve defect

17

Hydrocephalus

associated with 80% of midline brain tumors due to obstruction of ventricular system

- initial symptoms are early morning intermittent headaches and nausea/vomitting

- most resolve after mass resection but 15% require shunt or ventriculostomy

18

Intracranial Pressure triad

AM headaches, Nausea and vomitting, Lethargy

Other signs are bulging fontanelle, sundowning eyes

19

Most common childhood tumor

Low Grade (Pilocytic) Astrocytoma

Low grades are grade I and II and are typically benign
grade III is anaplastic and
grade IV is GBM

20

Low Grade Astrocytoma survival rate

- Good if total resection is achieved

21

EOSINOPHILIC ROSENTHAL FIBERS

Juvenile Pilocytic astrocytoma

22

Second most common type of peds tumor

medulloblastoma: arises in primitive nerve cells

- If formed in cerebrum it is a primitive neuroectodermal tumor

- Cerebellar : medulloblastoma

23

Peak age of medulloblastoma

3-4 yrs

24

Medulloblastoma is generally highly malignant, can compress the 4th ventricle

ok

25

Homer Wright Rosettes?

Small blue cells seen in a circular patter surrounding a fibrilliar area.....Medulloblastoma

26

Brainstem glioma prognosis

Prety much all fatal. surgery contraindicated, Just perform supportive care

27

Diffuse intrinsic pontine glioma

- dismal prognosis
- median age is 7
- Corticospinal weakness and CN 6,7,8 deficits

Tumor will engulf the basilar artery on MRI

28

Ependymoma

Arise from edendymal linings of ventricles....commonly 4th ventricle

29

Perivascular psuedorossetes?

Edendymomas

30

Try to avoid radiating the brain until what age

3yrs...axonal growth and synaptogenesis heavy in first three years

Rate of growth and dvelopment slows after age 6 so delaying until age 7 is even better

31

Radiation effects

intellectual impairment, memory, cognitive