G10 DNA(Slides Summary) Flashcards

(33 cards)

1
Q

monomers of nucleic acids

A

nucleotides

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2
Q

components of nucleotides

A

a five-carbon sugar
a phosphate group
a nitrogenous base

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3
Q

strand of nucleic acids is formed by linked nucleotides together by

A

phosphodiester bonds

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4
Q

DNA strand has a _ _ where the phosphate group is found

A

5’ end

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5
Q

DNA strand has a _ _ where the sugar molecule is located

A

3’ end

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6
Q

Double helix is _ - handed

A

right

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7
Q

The double helix twissts in the clockwise direction which results in the formation of major and minor _.

A

grooves

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8
Q

The DNA sequence can be represented by its nitrogenous bases.

A
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9
Q

are nucleic acids involved in protein synthesis

A

Ribonucleic acid (RNA)

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10
Q

Ribonucleic acid (RNA) are nucleic acids involved in protein synthesis. It uses _ instead of thymine as one of its nitrogenous bases.

A

uracil

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11
Q

a principle that the genetic information contained in the DNA is replicated and transferred to RNA molecules that direct the synthesis of protein molecules

A

central dogma of molecular biology

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12
Q

a semiconservative process wherein DNA molecules are duplicated during cell division and passed on to each daughter cell.

A

Replication

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13
Q

involves unwinding and unzipping by the helicase and the stabilization by the topoisomerase and SSBPs

A

Initiation of replication

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14
Q

involves the continous and discontinous synthesis in the leading and lagging strands by the DNA polymerase III

A

Elongation stage (of replication)

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15
Q

occurs when the two strands are already bound to each other. DNA polymerase I replaces primers, and DNA ligase seals the gaps.

A

Termination of replication

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16
Q

The cell has no 100%-accurate replication machinery. However, it has proofreading and mismatch repair mechanisms.

17
Q

are involved in the translation and transcription of genetic information in DNA

A

Ribonucleic acids or RNAs

18
Q

Ribonucleic acids contains uracil instead of _.

19
Q

process of converting the genetic information in DNA to synthesize mRNA

A

Transcription

20
Q

three types of RNA

A
messenger RNA (mRNA)
transfer RNA (tRNA)
ribosomal RNA (rRNA)
21
Q

is the enzyme responsible for synthesizing the complementary RNA called primary transcript

A

RNA polymerase

22
Q

RNA polymerase is the enzyme responsible for synthesizing the complementary RNA called

A

primary transcript

23
Q

Transcription starts at

A

promoter region

24
Q

Transcription ends in

A

terminator sequence

25
Transcription starts at the promoter region and ends in the terminator sequence. The mRNA detaches to form a
hairpin structure
26
_ _ of the pre-mRNA involves splicing to remove introns and the addition of 5’ cap and 3’ poly-A tail
Post-transcriptional modification
27
Post-transcriptional modification of the pre-mRNA involves splicing to remove _ and the addition of 5’ cap and 3’ poly-A tail.
introns
28
Post-transcriptional modification of the pre-mRNA involves splicing to remove introns and the addition of 5’ _ and 3’ poly-A _.
cap, tail
29
involves the formation of the translation complex consisting of the mRNA, 70S ribosome, and the initiator tRNA
Initiation of translation
30
involves the cycle of entry into A site and exit through E site by the tRNAs
Elongation of translation
31
Elongation involves the cycle of entry into A site and exit through E site by the tRNAs. The _ _ elongates in this stage.
polypeptide chain
32
involves the recognition of one of the three stop codons (i.e., UAA, UAG, or UGA).
Termination of translation
33
three stop codons
UAA UAG UGA