Flashcards in GI Pathology Deck (51)
Failure of lower esophageal sphincter (LES) to relax; loss of ganglion cells.
Hernia of the stomach into the chest through the diaphragm.
Esophageal varices are dilated veins in the _____ esophagus. Seen in what?
Chronic inflammation of the lower esophagus due to acid regurgitation.
Gastro-esophageal reflux disease
Premalignant metaplastic change of lower esophagus due to GERD.
MC esophageal cancer: Show excess _______ in the diet.
Squamous cell carcinoma
Esophageal cancer: Adenocarcinoma comes from?
Linear tear in lower esophagus due to protracted vomiting and retching.
Peptic ulcer disease is due to a ______ infection.
Peptic ulcer presents with an ulcer along the ________ of the stomach - 70% of the time or on the _____95%.
Lesser curvature - 70%
Duodenum - 95%
Epigastric pain is _____ with meals in gastric/stomach and _____ with duodenal ulcers.
Greater - gastric
Decreases - duodenal
Young male infant, projectile vomiting, hypertrophic pylori sphincter
Congenital pyloric stenosis.
Atrophic gastritis is caused by _____ infection. Predisposition to _______ and ________.
Pernicious anemia (B12)
What can cause a gastric carcinoma?
H pylori infection
High nitrosamines in diet
Gastric carcinoma is MC in what area of stomach?
Unexplained weight loss is seen in gastric carcinoma as well as Troisier's sign which is:
Metastatic lymph node in the left supraclavicular fossa (node is known as Virchow's node)
Non-caseous granuloma, cobblestone terminal ileum, skip lesions, and fistula.
Crohn's disease aka
Meckel's diverticulum is a remnant of?
What are the 2's of Meckel's diverticulum?
2' proximal to the ileocecal valve
2% of people
2x's MC in males
2 types of tissue: gastric and pancreatic
Celiac disease aka? Due to malabsorption of?
Whipple's disease aka?
Tropical sprue/Whipple's disease caused by? Results in?
trophermya whipplei (gram+ rod)
steatorrhea and arthritis
Appendicitis is inflammation of the appendix following blockage of it's lumber by a ______.
Appendicitis: periumbilical pain radiation to the ____ pain with tenderness at ________ point.
Diverticulis is inflammation in the diverticulum in the _____. MC in _______. Causes _____ pain and blood in stool.
Telescoping of a proximal part of bowel into a distal segment. Presents with abdominal pain and intestinal obstruction in a _____.
Arrested neural crest cell migration, congenital aganglionosis of the _______ colon. Present with chronic constipation and a distended abdomen in _____. What is it?
Chronic ulcerative inflammation. Present with bloody diarrhea, toxic megacolon, and an increased risk of colon CA.