Flashcards in Musculoskeletal - Benign Bone disorders Deck (43):
Loss of bone quantity while bone quality is normal.
Senile type of osteoporosis is MC in _____ and due to lack of ________
Loss of bone quality with softening of the bone.
Looser's zones on x-rays of bones.
Loss of bone quality in children, bowlegs and Rachitic rosary (swollen costochondral joints) decrease vitamin D
Brown (hemosiderin) bone cysts and hypercalcemia due to hyperparathyroidism.
osteitis fibrosa cystica
Reduced bone mineral density, age, postmenopausal women, nutrient deficiency, much worse in women.
Osteoporosis MC fracture sites:
Vertebral body compression
Osteolysis followed by deposition of disorganized bone, enlarged bone that lacks strength, "shaggy" appearance.
Shows up on x-ray with "Ivory vertebra" and also seen axial skeleton, femur, skull, pelvis and has fractures and nerve compression.
Disruption of vascular supply to bone (fracture), bony necrosis, hip and shoulder.
Arrested development of bone, bone softening, most sever when involving multiple bones (polyostotitc), femur (Shepard's crook), craniofacial distortion, sever distortion.
Polyostotic dysplasia, café-au-lait spots precocious puberty (endocrinopathy).
Malignant, adolescent, Caucasians, femur, pelvis, periosteal reaction (onion skinning)
Bone marrow infection, S. aureus, M tuberculosis, involucrum
Pronounced ankylosis on the anterior segment of vertebral bodies, common on anterior cervical vertebrae, "flowing ossification" or "melted candle wax", idiopathic, diabetes.
Diffuse Idiopathic Skeletal Hyperostosis (DISH)
Benign, round lesion, smaller than 2 cm in diameter, subcortical, central nidis (radiolucent), pain, nocturnal pain that is relieved by aspirin.
Malignant, aggressive, adolescents, periosteal reaction (Codman's triangle, sunburst), metaphyseal region of long bones, very common around knee, amputation.
MC bone forming tumor in adolescents.
Benign, large cartilage-capped outgrowth, metaphysics, males, age 10-30, slow growing, cortex merges, common around knee
Several osteochondromas called?
Multiple hereditary exostosis
Benign, circular lucency with a narrow ring of sclerosis, almost always in hands.
Multiple enchondromas of the hand
Malignant, periosteal reaction (thinning or thickening), adult males, pelvis, shoulders, may develop inside medullary cavity and may expand into surrounding soft tissue (palpable mass)
Fibroblast growth factor receptor gene mutation, shortening of long bones, frontal bossing, Midvale hypoplasia, bullet vertebrae, central spinal canal stenosis.
Brittle bone disease, abnormal type I collagen, affects all extracellular matrix, weak bones, skin, joints, irregular teeth, hearing loss.
Stone bone, dysfunctional osteoblasts, marrow fills, fractures, cranial nerve palsied, Erlenmeyer flask deformities.
MC degenerative joint disorder.
Degenerative joint disorder, altered articular cartilage, age-related, trauma, infection may accelerate, associated with subchondral cysts, Herberden nodes
Gout MC in
Gout is abnormal _____ metabolism.
Gout: Uric acid crystals in synovium called?
Gout MC in ______ (pdagra)
Calcific tendonitis, hydroxyapatite deposition into the tendons, idiopathic, 40-70 yrs old, reduced range of motion, pain, swelling
Hydroxyapatite deposition disease
HADD MC involves what?
Rotator cuff muscles (supraspinatus)
Phosphate deposition into cartilage, knee, wrist, faint Calcific appearance in joint space, elderly.
Calcium pyrophosphate deposition disease CPPD
Borrelia burgdorferi from lxodes deer tick, early bullseye rash (erythema chromium migrans
Aggressive skeletal muscle cancer, children, head, neck. What cells?
Malignant smooth muscle tumor, uterus (females), cigar shaped nuclei
Benign smooth muscle tumor. Uterine fibroids, small intestine