Flashcards in GI13 Deck (20):
What is Achalasia?
Failure of relaxation of lower esophageal sphincter (LES) due to loss of Myenteric (Auerbach's) plexus.
What do you see on a barium swallow in a patient with Achalasia?
Dilated esophagus with an area of distal stenosis
Achalasia is associated with an increased risk of what cancer?
Secondary Achalasia is associated with what?
Gastroesophageal reflux disease (GERD).
-Presents as heartburn and regurgitation upon laying down
-May present with nocturnal cough, dyspnea
-DECREASE in LES tone
-Dilated submucosal veins in lower 1/3 of esophagus
-Secondary to Portal HTN
Mucosal lacerations at the GastroEsophageal junction d/t VOMITING
-leads to hematemesis
-Seen in Alcoholics and Bulimics
Transmural esophageal rupture d/t VIOLENT retching.
Associated with lye ingestion and acid reflux
-Dysphagia (d/t esophageal webs)
-Iron deficiency anemia
-replacement of nonkeratinized (stratified) squamous epithelium with intestinal (nonciliated columnar) epithelium in the distal esophagus
What causes Barrett's esophagus?
What is Barrett's esophagus associated with?
-Increased risk of esophageal Adenocarcinoma
What are the risk factors for Esophageal cancer?
Achalasia - SCC
Alcohol - Adeno
Barrett's - Adeno
Ciggys - Both
DIverticula - SCC
Esophageal web - SCC
Fat - Adeno
GERD - Adeno
Hot liquids - SCC
Where do you typically see SCC of the esophagus?
*Most common WORLD WIDE