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FA - GastroIntestinal > GI25 > Flashcards

Flashcards in GI25 Deck (17):
1

Acute pancreatitis:
- Causes

Autodigestion of pancreas by pancreatic enzymes

-Idiopathic
-Gallstones
-Ethanol
-Trauma
-Steroids
-Mumps
-Autoimmune
-Scorpion
-Hypercalcemia
-Hypertriglyceridemia (>1000)
-ERCP
-Drugs

"GET SMASHED"

2

Acute pancreatitis:
- Clinical presentation

-Epigastric abdominal pain (RADIATES to back)
-Anorexia
-Nausea

3

Acute pancreatitis:
- Labs

-Elevated amylase
-Lipase (higher specificity)

4

Acute pancreatitis:
- Main complication

Pancreatic pseudocyst

5

What is a pancreatic pseudocyst?

-Line by granulation tissue
-Not epithelium
-Can rupture and hemorrhage

6

Chronic pancreatitis:
- Findings

-Chronic inflammation
-Atrophy
-Calcification of the pancreas
-Can lead to pancreatic insufficiency

7

Chronic pancreatitis
- Causes

-Alcohol abuse
-Idiopathic

8

S/S of pancreatic insufficiency.

-Steatorrhea
-Fat-soluble vitamin deficiency
-Diabetes mellitus
-INcreased risk of pancreatic adenocarcinoma

9

Chronic pancreatitis:
- Labs

-Elevated amylase
-Lipase

*LESS Elevated compared to Acute pancreatitis

10

Pancreatic adenocarcinoma:
- General characteristics

-Prognosis 6 months or less
-Tumor arising from Pancreatic Ducts
-Usually already mets at presentation

11

Pancreatic adenocarcinoma:
- Common tumor site

Head of pancreas (obstructive jaundice)

12

Pancreatic adenocarcinoma:
- Tumor markers

-CA-19-9 tumor marker
-CEA (CarcinoEmbryonic Ag)

13

Pancreatic adenocarcinoma:
- Risk Factors

-Tobacco use (NOT EtOH)
-Chronic pancreatitis (especially > 20 years)
-Age > 50 years
-Jewish and African-American MALES

14

Pancreatic adenocarcinoma:
- Often presents with

-Abdominal pain radiating to back
-Weight loss
-Migratory thrombophlebitis
-Obstructive jaundice with palpable, nontender gallbladder

15

Pancreatic adenocarcinoma:
- Treatment

-Whipple procedure
-Chemotherapy
-Radiation therapy

16

Courvoisier's sign.

Obstructive jaundice w/:
-Palplable
-Nontender gallbladder

17

Trousseau's syndrome.

Migratory thrombophlebitis:
-Redness and tenderness on palpation of extremitites