Glomerulonephritis 2 Flashcards Preview

Renal > Glomerulonephritis 2 > Flashcards

Flashcards in Glomerulonephritis 2 Deck (27)
1

Commonest cause of nephrotic syndrome in children

Minimal change nephropathy

2

Treatment for minimal change nephropathy

1st line: steroids
2nd line: cyclophosphamide

3

Will minimal change lead to progressive renal failure?

No

4

Commonest cause of nephrotic syndrome in adults

FSGS
(focal segmental glomerulosclerosis)

5

Follow HIV/heroin use/obesity/reflux nephropathy

FSGS
(focal segmental glomerulosclerosis)

6

Will FSGS progress to end stage renal failure?

Yes, 50% will have within ten years

7

Treatment for FSGS

Steroids

8

Important causes of membranous nephropathy?

Infections (hep B/parasites)
CTDs (lupus)
Malignancies (carcinoma/lymphoma)
Drugs (gol, penicillamine)

9

Drugs which could cause membranous nephropathy?

Gold, penicillamine

10

Infections which could cause membranous nephropathy?

Hep B, Parasites

11

CTDs which could cause membranous nephropathy?

Lupus

12

Malignancies which could cause membranous nephropathy?

Carcinoma, lymphoma

13

Type of GN that follows HepB

Membranous

14

Type of GN associated with CTDs

Membranous

15

Type of GN that occurs in gold/penicillamine use

Membranous

16

Could you progress to end stage renal failure following membranous nephropathy?

Yes, 30% progress

17

Treatment for membranous nephropathy

Steroids/alkylating agents/B cell monoclonal antibody

18

Nephropathy that follows resp/GI infection

IgA nephropathy

19

Nephropathy associated with AKI/CKD

IgA nephropathy

20

Nephropathy associated with HSP

IgA nephropathy

21

Mesangial cell proliferation and expansion on light microscopy with IgA deposits in mesangium on IF

IgA nephropathy

22

Subepithelial imune complex deposition in the basement membrane

Membranous nephropathy

23

Does IgA nephropathy progress to ESRF?

Yeah, 25%

24

Management of IgA nephropathy?

BP control/ACEi/ Fish oil

25

RPGN associated with _____ on biopsy

Glomerular crescents

26

Type of nephropathy associated with vasculitis?

RPGN

27

Treatment for RPGN

Immunosuppression
Steroids (IV Methylprednisolone / Oral Prednisolone)
Cytotoxics (Cyclophosphamide/ Mycophenolate/ Azathioprine

Plasma phoresis