Haldol

Question 1

Haloperidol

Class

Answer 1

• Tranquilizer
• Antipsychotic

Question 2

Haloperidol

MOA

Answer 2

• Inhibits CNS catecholamine receptors
• Strong antidopaminergic & weak anticholinergic
• Acts on CNS to depress subcortical areas, midbrain, and ascending reticular activating system in the brain

Question 3

Haloperidol

Indications

Answer 3

• Acute psychotic episodes

Question 4

Haloperidol

Contraindications

Answer 4

• Agitation secondary to shock or hypoxia
• Hypersensitivity

Question 5

Haloperidol

Adverse reactions

Answer 5

• Extrapyramidal S&S
• Restlessness
• Spasms
• Parkinson-like symptoms
• Drooling
• Dystonia
• Hypotension
• Orthostatic hypotension
• N/V
• Blurred vision

Question 6

Haloperidol

Drug interactions

Answer 6

• Enhanced CNS depression and hypotension in combination with alcohol
• Antagonized amphetamines and epinephrine
• Other CNS depressants may potentiate effects

Question 7

Haloperidol

Dosage

Answer 7

• Adult:
  
  • 2-5 mg IM q 30-60 min until sedation achieved
• Not for peds

Question 8

Haloperidol

Duration of action

Answer 8

• Onset: 10 min
• Peak: 30-45 min
• Duration: variable (genarally 12-24 hrs)

Question 9

Haloperidol

Special Considerations

Answer 9

• Preg Cat: C
• Treat hypotension secondary to Haldol with fluids and norepi, not epi
• PT may also be taking Cogentin (benztropine mesylate) if on long-term therapy with Haldol