Diltiazem Flashcards Preview

Preg Cat: C > Diltiazem > Flashcards

Flashcards in Diltiazem Deck (9):
1

Class

  • Calcium channel blocker

2

MOA

  • Block calcium ions from going into cardiac muscle
  • Prevents spasm of coronary arteries
  • Arterial and venous vasodilator
  • Reduces preload and afterload
  • Reduces myocardial oxygen demand

3

Indications

  • Control of rapid ventricular rates due to:
    • A-fib
    • A-flutter
    • Re-entry SVT
  • Angina pectoris

4

Contraindications

  • Hypotension
  • Sick sinus syndrome
  • 2nd & 3rd deg AV blocks
  • Cardiogenic shock
  • Wide-complex tachycardias
  • Poison & drug induced tachycardia

5

Adverse reactions

  • Bradycardia
  • 2nd or 3rd deg AV blocks
  • CP
  • CHF
  • Syncope, dizziness, dyspnea
  • V-fib, V-tach
  • N/V, HA, dry mouth

6

Drug Interactions

  • Beta-blockers
  • Use caution with meds that affect contractility

7

Dosage

  • Adult:
    • Initial bolus 0.25 mg/kg IV over 2min
      • (average dose 15-20mg)
    • May rebolus in 15 min at 0.35 mg/kg
    • Maintenance infusion 5-15 mg/hr
  • Not for peds

8

Duration

  • Onset:  2-5 min
  • Peak: varies
  • Duration:  1-3 hrs

9

Special Considerations

  • Preg Cat: C
  • Use caution in pts with:
    • renal failure
    • hepatic failure
  • PVC's may be seen during conversion to sinus rhythm