Flashcards in Hemonc 412,413 Deck (17)
What are the 2 most commonly used glucocorticoids in cancer chemotherapy?
Diabetic retinopathy is treated with what Monoclonal antibody?
Bevacizumab -> anti- VEGF
Tx of Adenocarcinoma of the lung and MOA?
Erlotinib: EGFR tyrosine kinase inhibitor
Rituximab inhibits which CD?
Pt that has been treated with BCR-ABL mutation presents with edema, what was the Tx?
Imatinib - Fluid retention.
What drug would you use to treat a 68 year old female with breast ca?
Raloxifene, useful to prevent osteoporosis.
HER-2 (c-erbB2) is what kind of receptor?
tyrosine kinase receptor
Which Tx blocks the binding of estrogen to ER ⊕ cells?
(SERMs)—receptor antagonists in breast
Tx and MOA that treats Metastatic melanoma?
Small molecule inhibitor of BRAF oncogene ⊕ melanoma
Which anti-inflam drugs can cause cataracts, acne, hypertension, peptic ulcers and psychosis?
Pt undergoing Tx for B-cell neoplastic presents with nonenhancing areas of demyelination on MRI. What was the Tx that caused this?
Rituximab due to developement of progressive multifocal leukoencephalopathy
Toxicity of Herceptin?
SE: of EGFR tyrosine kinase inhibitor?
(SERMs)—receptor antagonists of the breast causes an incr risk of endometrial cancer?
This drugs SE are similar to a dz that is caused by shistosomiasis?
CYclophosphamide--> hemorrhagic cystitis
Pt in chemotherapy acquires hearing loss, what was the Tx?