Hemorrhagic fever viruses Flashcards Preview

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Flashcards in Hemorrhagic fever viruses Deck (14):
1

mechanism of 2nd infection w/dengue fever

 

presentation of 2nd infection w/dengue fever

antibodies from 1st dengue fever infection cross-react with new dengue infection; Fc receptor on these antibodies are taken to mononuclear cells where dengue infects!

 

2nd infections are more sever and can cause dengue hemorrhagic fever or dengue shock sydnrome

1

most common hantavirus strain WW; disease manifestation?

hantaan virus

hemorrhagic fever and renal syndrome(HFRS)

over 100000 cases in china; 5-10% mortality

2

bunyaviridae virus 

 

most common strain in US and its disease??

hantavirus, sin nombre virus

 

hantavirus pulmonary syndrome(HPS) - severe pulmonary illness w/fever; acute respiratory distress

3

transmission of hantavirus

  aerosol of urine/feces from rodents

 

3

ebola structure/genome

ssRNA(-), helical, enveloped

4

transmission of:

yellow fever, dengue

hantavirus, lassa virus

yellow fever and dengue - mosquito

hantavirus - rodent urine/feces 

lassa - house rat urine/feces

5

clinical presentation of lassa virus

multi-organ system disease w/fever and hemorrhaging

 

kinda looks like ebola

7

leading cause of acute febrile illness in US travelers returning from: carribbean, south america, and asia

dengue fever

8

viruses causing hemorrhagic fever

yellow fever, dengue (flavi)

hantavirus(buny)

Lassa(arena)

ebola(filo)

9

lassa virus transmission

house rat

human-human spread is possible too

10

clinical presentation of yellow fever

"black vomit" - hematemesis

Hepatitis(yellow) + hemorrhagic fever

 

12

vaccines available for hemorrhagic fever viruses?

just yeloow fever(live-attenuated, effective)

13

treatment for lassa virus

ribavirin

14

lassa virus genome

 

family of lassa virus?

ssRNA(-), segmented(2)

 

arena virus