Histology - GI Development Flashcards Preview

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Flashcards in Histology - GI Development Deck (32)
1

Liver, Gall Blader, and ventral part of pancreas derived from

Ventral Bud

1

Omphalocele

no umbilical hernia reduction, mass may include foregut structures, high rate of mortality

2

RA high Caudally

RA Concentration Gradient

2

Hypertrophic pyloric stenosis

Smooth muscle hypertrophy/hyperplasia

3

ilial diverticulum. ~2% of population, ~2 inches long, ~2 feet from ileocecal junction

2X2X2 rule

4

270 degree purpose

Places small intestin within loop of large intestine

6

not gut tube. From Visceral Mesoderm, intraperitoneal.

Spleen derivation

7

Biliary duct atresia

Failure of duct to recanalize. Intrahepatic: generally fatal, Extrahepatic: often correctable

7

Annular pancreas

Ventral bud encircles the duodenum. May constrict/occlude duodenum.

7

Colorectoanal atresia

imperforate anus

9

rectum & proximal anus

Anorectal canal

10

Midgut developmental events

Week 5 - Week 12. Physiological umbilical herniation, 270 degree counterclockwise rotation, differential growth

11

Pancrease source

Dorsal Pancreatic Bud

13

prolifertation of epithelium that closes the lumen. Completes by week 5

Occlusion

14

SHH & HOX

Concentric layering of the gut tube

15

Distal anus derived from

ectoderm, separated by pectinate line

16

malrotation

Left-sided colon, reverse intestinal rotation

17

90 CCW rotation only

Left-sided colon

18

greater omentum

Dorsal mesogastrium - bloody supply

18

Physiological umbilical herniation purpose

Accomodates expanding liver & gut tube

19

Reversed intestinal rotation

90 CCW, 180 CW - places large colonbehind duodenum.

20

Jejunal, ileal stenoses/atresia

Ischemic necrosis, herniation, volvulus (twisting)

21

Connects intestinal loop to yolk sac

Vitelline duct

22

Growth induced reopening of the lumen - completes by week 9

Recanalization

24

hindgut fistulas

Rectoperineal fistula, Colovaginal (rectovaginal) fistula, Colovesical (urorectal) fistula

25

falciform ligament & lesser omentum

Ventral mesogastrium - liver budding, ends at umbilicus

26

RA & HOX

Cephalocaudal differentiation

27

SHH High in Lumen

SHH Concentration Gradient

28

Remnant of vitelline duct, generally asymptomatic, but may present like appendicitis.

ileal (Meckel’s) diverticulum

30

Urorectal septum forms

dividing cloaca into anorectal canal and urogenital sinus.

31

Esophageal, gastric, duodenal stenoses/atresias

Improper recanalization - epithelial issue

32

hernia due to anterior body wall defect, mass not within umbilicus, lower mortality

Gastroschisis