Human Bio Unit 1 - Cystic Fibrosis

Question 0

Cause

Answer 0

Mutation to the gene that make a channel protein

Mucus can’t becomes sticky and can’t be dislodged and restricts airways

Question 1

Symptoms of CF

Answer 1

Coughs

Repeated chest infections

Prolonged diarrhoea

Poor weight gain

Question 2

What the mutated channel protein should do

Answer 2

Protein pumps chloride ions out of the epithelial cells to lower the water potential of mucus and allows it to be removed by cilia

Question 3

Effects of CF on the pancreas

Answer 3

Stops it digesting starch properly because it blocks the pancreatic duct

Question 4

What is the type of mutation that causes CF?

Answer 4

Deletion

Question 5

What does the gene that people with CF don’t have code for?

Answer 5

CFTR prtein

Question 6

What type of pancreatic does CF cause?

Answer 6

Chronic

Question 7

Symptoms of CF?

Answer 7

Coughs

Repeated chest infections

Prolonged diarrhoea

Poor weight gain

Question 8

How can CF be treated?

Answer 8

Physiotherapy

Exercise

Medication

Nutrition

Question 9

What causes the CFTR protein to not function properly?

Answer 9

Wrong shape and does not get inserted in the membrane

Question 10

Why do CF sufferers need to eat a highly nutritious diet?

Answer 10

Mucus blocks pancreatic duct and causes reduction in secretion of enzymes so less digestion of food

Thick mucus reduces absorption of products of digestion