Imaging in inflammatory disorders and infection Flashcards Preview

Principles of disease JK > Imaging in inflammatory disorders and infection > Flashcards

Flashcards in Imaging in inflammatory disorders and infection Deck (11):
1

Molecular imaging

Radionuclide imaging eg PET
Radioactive element and pharmaceutical element

2

PET

Cyclotron produced isotopes with extremely short half lives and emit positrons
Bump particles with oxygen rich water and combine with ligand

3

What does PET show?

Physiological function of organs

4

PET tracer

Gamma emitted by positron - emitting radionuclide

5

FDG

Radiotracer used to show tissues that use glucose

6

Ideal isotope for labelling (5)

- Half life similar to length of examination
- Gamma emitter
- Energy 50-300keV
- Readily available radionuclide
- Easily bound to pharmaceutical component

7

Gamma radiation

Occurs due to radioactive decay of unstable isotope and has a high frequency and energy

8

Gamma camera ENERGY

Nuclear => Gamma => light EM => electrical
(nucleus from patient image crystal to display)

9

SPECT

CT version of nuclear medicine ( tracer used)

10

What does SPECT look at?

Brain and cardiac studies using roatating gamma cameras

11

What does SPECT show?

Blood flow