Immunology Flashcards
(55 cards)
What is the difference between Cytokines and chemokines
cyTokines = pleioTropic = mulTiple jobs = acTivaTes other cells
where as chemokines don’t and there is no T
____ mainly reside in the tissues and ____ mainly circulate in blood
Macrophages, neutrophils
what contributes to an inflammatory response
Brain, muscle, liver
Neutrophil levels increase in the blood after exercise due to increased:
Blood flow
Obesity can be considered an inflammatory disease because
There are more inflammatory molecules in obese people compared to healthy people
T/F
Cell recognise both PAMP and DAMPS via pattern recognition receptors
TRUE
The cells most responsible for resolving inflammation are
Macrophages
both acute inflammation (infection) and systemic inflammation (obesity): The disease process is mediated by______
cytokines
The role of chemokines in inflammation is to
Recruit immune cells to the site of infection
What is the effect of inflammation:
• Swelling
• Redness
• Heat pain
what are the three different types of inflammation responses to infections
- acute
- chronic
- systemic
what is an acute response
Fast, occurs w/ injury, resolves (heals)
what is a chronic response
long term, disease process/injury, unresolved
what is a systemic response
long term, Low level, unresolves
how do you get immune response
if cell is able to detect self and dangerous infection
Where to macrophages grow
in bone marrow
macrophages live in the blood as ___
monocytes
what is the function of macrophages
Phagocytose(take out) and destroy)
macrophages are able to ____ and ___ other immune cell
activate and recurit
Neutrophils grow in
the bone marrow
Neutrophils are able to rapidly …
produce in bone marrow after infection or injury
Neutrophils are cells that engulf…
• Cells that engulf all the bacteria
T/F macrophages have receptors to detect
true
what are the two main roles of neutrophil fighting pathogen
• Phagocytosis (eating them)
• Degranulation (release toxic chemicals)
