lab 9 & 10 Flashcards

(53 cards)

1
Q

what do your cells uses glucose for

A

create ATP

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2
Q

what is the normal range for fasting blood glucose

A

4-6mmol/L

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3
Q

what did we find from lab 10 - results from blood glucose concentration with glucose spit

A

expect blood glucose to decrease over time

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4
Q

if you fasted for 12hrs what would this mean for glucose concentration

A

would stay consent

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5
Q

what did we find from lab 10 - results from blood glucose concentration with glucose drink

A

insulin will simulate the pancreas, take time for glucose to go into blood - glucose levels rise over time

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6
Q

what did we find from lab 10 - results from blood glucose concentration with exercise

A

glucose levels drops over time

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7
Q

why is important for the blood glucose to be kept within that range (4-6)

A
  1. so cells always have full they need to make ATP
  2. important it is not too high - or else will cause damage to cells
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8
Q

when fasting what hormone is released when blood glucose drops below normal range

A

glucagon

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9
Q

when fasting which organ and which cells glucagon is released from

A

alpha cells from pancrease

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10
Q

what tissues are target cells for glucagon hormone

A

liver

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11
Q

when bound to receptors on alpha cells what effect does glucagon hormone have

A
  • liver breaks down glucose
  • make more glucose, to release into blood stream, to increase blood glucose levels
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12
Q

what turns off rlease of glucogon hormone

A

pancrea stops secreting glycagon when blood glucose increases and returns to normal

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12
Q

what turns off release of glucagon hormone

A

pancreas stops secreting glycagon when blood glucose increases and returns to normal

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13
Q

if you sip of spit out glucose solution (lab 10) - blood glucose may have decreased from baseline why?

A
  • brain receives signals from taste receptor detect glucose
  • stimulates brain to activate insulin hormone release from pancreas - w/ anticipation
  • insulin signals cells take glucose out of blood to reduce concentration
  • feedforward control
  • cephalic phase (brain)
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14
Q

if you exercise in lab 10, blood glucose may have decreased why?

A
  • cells using more glucose
  • take out glucose - less in blood
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15
Q

if after drinking glucose drink blood glucose levels increased above normal range - which hormone is released

A

insulin

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16
Q

if insulin is released which organ and cells is this released from

A

pancrease, beta cells

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17
Q

which target cells have receptors for insulin hormone

A

all body cells

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18
Q

when bound to to receptors on beta cells what effect does this insulin hormone have

A

insulin stimulates glucose out of blood to use
- livers and skeletal all store glucose as glycogen and adipose cells store glucose as fat

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19
Q

what turns off release of insulin

A

as blood glucose decrease, returns to normal - pancreas stops secreting insulin

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20
Q

what hormones increase blood glucose

A

glycogon, adrenalin, cortisol, growth

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21
Q

what is the only hormone decrease blood glucose

22
Q

what is the stimulus and effect of glugacon

A

glucose is gone
stimulus: low blood glucose
effect: increase blood glucose

23
Q

what is the stimulus and effect of insulin

A

stimulus: high blood glucose
effect: decrease blood glucose

24
what is the stimulus and effect of TRH
stimulus: cold stress/exercise effect: stimulus release of TSH from anterior pituitary gland
25
what is the effect of TSH
stimulates release of thyroid hormone from thyroid gland
26
what is the effect Thyroid hormone
increase cellular metabolism - all cells to work faster
27
what is the stimulus and effect of GHRH
stimulus: sleep/ exercise effect: release GH from anterior pituitary
28
what is the effect of GH (2)
1. increase fuel in blood (glucose, fatty acids) 2. release IGF-1 from liver
29
what is the effect of IGF-1
increase growth tissue
30
what is the stimulus and effect of adrenaline
stimulus: short-term stress/exercise effect: increase HR, BP, and fuel
31
what is the stimulus and effect of ADH
stimulus: stress/exercise and increase ECF osmolarity (dehydration) effect: causes kidney to reabsorb more water back into the blood
32
what is the stimulus and effect of CRH
stimulus: chronic stress/ or normal day -nigh rhythm effect: release ACTH
33
what is the effect of ACTH
release of cortisol from adrenal gland
34
what is the effect of cortisol
long term stress respons, increase fuel sources (glucose, fatty acid, AA), BP, immunity
35
hypothalamic neurons to
sympathetic neurons
36
sympathetic neurons connect to
adernal medulla (middle of medulla)
37
adernal medulla causes the release of
adrenaline
38
hypothalamic nurons axons reach down into what gland
posterior pituitary gland
39
posterior pituitary gland releases
ADH - no peeing, making kidney cells reabsorb more water back into blood
40
what is the off signal for glugacon
increase glucose
41
what is the off singal for insulin
decrease glucose
42
what is the off signal for TRH
warm up or stop exercise. TSH and TH negative feedback
43
what is the off signal for TSH
no more TRH, TH negative feedback
44
TH off signal
no more TSH
45
what is the off signal for GHRH
stop sleeping, stop exercise - GH and IGF-1 negative feedback
46
what is the off signal for GH
no more GHRH - increasing GHIH, IGF-1 negative feedback
47
what is the off signal for IGF-1
no more GH
48
what is the off signal for adrenaline
remove stress or stop exercising
49
what is the off signal for ADH
remove stress or stop exercising or rehydrate
50
what is the off signal for CRH
change time of day or remove stress - ACTH and cortisol negative feedback
51
what is the off signal for ACTH
no more CRH - cortisol negative feedback
52
what is the off signal for cortisol
no more ACTH