Ind Seminar 2.0 Flashcards
(51 cards)
What is the highest risk surgery for VTE?
Total knee replacement (TKR)
What does the Virchow triad consist of?
Stasis, Hypercoagulability, Endothelial injury
Classic signs of DVT?
Unilateral calf swelling, erythema, tenderness, pain on passive dorsiflexion
What score is used to assess DVT probability?
Well’s score
What investigation excludes VTE?
D-dimer test
What imaging confirms DVT?
Compression ultrasound or contrast venography
Initial treatment of DVT?
Heparin followed by oral anticoagulant
Monitoring frequency for heparin therapy?
Every 12 hours with coagulation profile
Target INR for warfarin therapy?
2-3
Clexane is contraindicated in?
Haram source (pig-derived)
Alternative to clexane?
Arixtra (fondaparinux)
Antidote for LMWH?
Protamine sulphate
How many stages are there in secondary fracture healing?
Five
First stage of secondary bone healing?
Haematoma formation
Second stage of bone healing?
Inflammation
Third stage of bone healing?
Soft callus formation
Fourth stage of bone healing?
Hard callus formation
Final stage of bone healing?
Remodelling
Main cytokines in bone healing?
BMP, IL-1, IL-6
Delayed union timeline for lower limb?
More than 12 weeks, up to 24 weeks
Non-union timeline?
More than 6 months without healing
Radiographic sign of delayed union?
Visible fracture line with incomplete callus
Definition of malunion?
Fracture heals in an unacceptable angulation
Causes of malunion?
Failure to reduce or hold reduction, collapse of bone