Msk Tumor 2.0

Question 1

What is the most common primary malignant bone tumor?

Answer 1

Osteosarcoma

Question 2

Which age group is most commonly affected by osteosarcoma?

Answer 2

Adolescents and young adults

Question 3

What are the common sites for osteosarcoma?

Answer 3

Metaphysis of long bones, especially around the knee

Question 4

Which imaging modality is first used to evaluate bone tumors?

Answer 4

X-ray

Question 5

What is the characteristic X-ray finding of osteosarcoma?

Answer 5

Sunburst appearance and Codman triangle

Question 6

What is the most common benign bone tumor?

Answer 6

Osteochondroma

Question 7

What is the usual age group affected by Ewing sarcoma?

Answer 7

Children and adolescents

Question 8

Which translocation is associated with Ewing sarcoma?

Answer 8

t(11;22)(q24;q12)

Question 9

What is the common presentation of bone tumors?

Answer 9

Pain and swelling

Question 10

Which bone tumors are most common in older adults?

Answer 10

Chondrosarcoma, metastatic bone disease

Question 11

What is the role of MRI in musculoskeletal tumors?

Answer 11

Staging and surgical planning

Question 12

What is the gold standard for definitive diagnosis of bone tumors?

Answer 12

Biopsy

Question 13

What is the typical treatment for benign bone tumors?

Answer 13

Observation or surgical excision if symptomatic

Question 14

What is the typical treatment for malignant bone tumors?

Answer 14

Combination of surgery, chemotherapy, and radiotherapy

Question 15

Which tumors are classified as cartilage-forming?

Answer 15

Osteochondroma, enchondroma, chondrosarcoma

Question 16

What is the hallmark of Ewing sarcoma on histology?

Answer 16

Small round blue cells

Question 17

What is the most common site of metastasis for osteosarcoma?

Answer 17

Lungs

Question 18

What is the most common site of metastasis to bone?

Answer 18

Spine

Question 19

What is the most common primary source of bone metastasis in males?

Answer 19

Prostate cancer

Question 20

What is the most common primary source of bone metastasis in females?

Answer 20

Breast cancer

Question 21

What is a characteristic feature of giant cell tumor on imaging?

Answer 21

Soap bubble appearance

Question 22

What age group is typically affected by giant cell tumor?

Answer 22

Young adults

Question 23

What type of lesion is an aneurysmal bone cyst?

Answer 23

Benign, blood-filled lesion

Question 24

What is the most common location for osteoid osteoma?

Answer 24

Femur and tibia

Question 25

What symptom is characteristic of osteoid osteoma?

Answer 25

Night pain relieved by NSAIDs

Question 26

What are the radiographic features of fibrous dysplasia?

Answer 26

Ground-glass appearance

Question 27

What syndrome is associated with multiple enchondromas and soft tissue hemangiomas?

Answer 27

Maffucci syndrome

Question 28

What is the Enneking classification used for?

Answer 28

Staging of musculoskeletal tumors

Question 29

What does a Codman triangle on X-ray suggest?

Answer 29

Aggressive periosteal reaction, often in osteosarcoma

Question 30

Which tumor presents with onion-skin periosteal reaction on X-ray?

Answer 30

Ewing sarcoma

Question 31

What is the role of CT in bone tumors?

Answer 31

Detailed bone anatomy and detection of metastasis

Question 32

Which tumor has a cartilaginous cap visible on imaging?

Answer 32

Osteochondroma

Question 33

What is the origin of chondrosarcoma?

Answer 33

Malignant tumor of cartilage-forming cells

Question 34

Which benign tumor can undergo malignant transformation?

Answer 34

Osteochondroma and enchondroma

Question 35

Which tumors are more likely in epiphysis?

Answer 35

Giant cell tumor and chondroblastoma

Question 36

What is the typical treatment for Ewing sarcoma?

Answer 36

Chemotherapy, surgery, and/or radiotherapy

Question 37

Which bone tumor is associated with Paget's disease?

Answer 37

Secondary osteosarcoma

Question 38

What is the typical presentation of metastatic bone disease?

Answer 38

Bone pain, pathological fractures

Question 39

What is the common site for chondroblastoma?

Answer 39

Epiphysis of long bones

Question 40

Which tumors show increased uptake on bone scan?

Answer 40

Osteosarcoma, metastases

Question 41

What is a nidus in osteoid osteoma?

Answer 41

Central radiolucent area surrounded by sclerosis

Question 42

What are the complications of untreated bone tumors?

Answer 42

Pathological fractures, metastasis, functional impairment

Question 43

What is the treatment for aneurysmal bone cyst?

Answer 43

Curettage and bone grafting

Question 44

What tumor shows a soap bubble appearance in the epiphysis?

Answer 44

Giant cell tumor

Question 45

Which tumor has a high risk of recurrence after curettage?

Answer 45

Giant cell tumor

Question 46

What is the common location of enchondroma?

Answer 46

Small bones of hands and feet

Question 47

Which bone tumors are radioresistant?

Answer 47

Chondrosarcoma

Question 48

What is the characteristic cytogenetic marker in Ewing sarcoma?

Answer 48

EWS-FLI1 fusion gene

Question 49

What is the typical management strategy for bone sarcomas?

Answer 49

Multidisciplinary approach

Question 50

Why is biopsy important before treating bone tumors?

Answer 50

To confirm histological diagnosis and plan treatment

Question 51

What imaging modality is best for soft tissue extension?

Answer 51

MRI