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Flashcards in Infections Deck (17):
1

What is the clinical presentation of acute BJI?

Pyrexia, systemic signs,
pain/swelling/redness
reduced mobility/movement of joint in flexed position
- in children they may not feed or play properly

2

Explain Systemic Inflammatory Response Syndrome (SIRS)

two or more of the following:
1. Pyrexia of 90
3. RR >20, PaCO2 12,000 or

3

How can Septic arthritis infection get in a joint space?

Haematogenous spread
Contigous spread (infected bone)
Direct inoculation (injection or trauma)
- Mainly MSSA, streptococci

4

How would you diagnose acute septic arthritis?

Blood culture if pyrexial
CRP, FBC, U&E, lactate, ESR etc.
Joint fluid aspirate
Crystals white cells and gram stain (gout, pseudogout)
Ultrasound, plain X-ray, MRI, CT, bone scan

5

How would you treat acute septic arthritis if the organism is Staph aureus?

IV Flucloxacillin (high dose)

6

How would you treat acute septic arthritis if the organism is H influenzae or Kingella (kids) ?

Ceftriaxone if they are under 5 years of age

7

What is Osteomyelitis?

Inflammation of bone and medullary cavity, usually long bones or vertabrae

8

What organisms can cause acute osteomyelitis?

MSSA or streptococci

9

What organisms can cause chronic osteomyelitis?

Myobacterium tuberculosis, pseudomonas aeriginosa, salmonella, brucella coliforms

10

How can Osteomyelitis spread?

Haematogenous
Contigous
Peripheral vascular disease associated
Prosthesis associated

11

Where is haematogenous spread most likely to occur in acute osteomyelitis?

Femur/tibia

12

How do you diagnose osteomyelitis?

Blood culture if pyrexial
bone biopsy,
emperic high doe flucloxacillin

13

What are risk factors for infection in prostethetic joints?

Rheumatoid arthritis
Diabetes
Malnutrition
Obesity

14

Where are coNS usually found?

As part of normal skin flora

15

How do you diagnose PJI?

Culture of tissue and bone
Blood culture
CRP, WCC
Radiological investigations

16

is Necrotizing fasciitis rapidly progressing?

YES

17

Describe Necrotizing fasciitis

Highly painful
spread through tissues very rapidly
systemic toxicity