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MSK > Muscle Disease > Flashcards

Muscle Disease Flashcards

1
Q

What is muscle pain?

A

Myalgia

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2
Q

How might a muscle disease present itself?

A

Myalgia, weakness/tiredness,
Stiffness
Abnormal blood tests

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3
Q

What are clinical features of Idiopathic Inflammatory Myopathies?

A

muscle weakness,
insidious onset
symmetrical, proximal muscles
sturggle with tasts e.g.difficulty brushing hair

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4
Q

What are indications of Dermatomyositis ?

A

Gottrons sign
Heliotrope rash
Shawl sign

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5
Q

What other organs are involved with Dermatomyositis?

A

Lung (ILD)
Oesophagus (Dysphagia)
Heart (myocarditis)

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6
Q

Name two tests that can be done, and what are they?

A
  1. Confrontational testing - direct testing of power

2. Isotonic testing - 30 second sit to stand test

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7
Q

What drugs can be used to treat Dermatomyositis

A 
Glucocorticoids
Azathioprine
Methotrexate
Ciclosporin
IV immunoglobulin
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8
Q

What can Inclusion body myositis be misdiagnosed as?

A

Polymyositis

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9
Q

Who’s more likely to get Inclusion body myositis ?

A

> 50’s

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10
Q

What drug can cause muscle pain?

A

Statin

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11
Q

What is the clinical appearance of Inclusion body myositis ?

A

More insidious onset
Distal muscle weakeness
Weakness in wrist, finger flexors in upper limbs and quads an anterior tibial muscles in legs

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12
Q

What does a muscle biopsy of Inclusion body myositis show?

A

Inclusion bodies

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13
Q

Who is more likely to suffer from Polymyalgia Rheumatica?

A

> 50’s

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14
Q

What are the clinical features of Polymyalgia Rheumatica?

A 
Shoulder and hip girdle pain
morning stiffness 
fatigue, anorexia, weight loss, and fever
reduced shoulder, neck and hip movement
Muscle strength is NORMAL
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15
Q

What is another name for Temporal Arthritis?

A

Giant cell arhtritis

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16
Q

What occurs with Temporal Arthritis ?

A 
Headache
Scalp tenderness
Jaw claudication
Visual loss (amaurosis fugax)
Tender, enlarged and non-pulsatile temporal arteries
17
Q

What investigation results are found with temporal arthritis?

A

Raised ESR
Plasma viscosity
CRP

18
Q

What is the treatment for temporal arthritis?

A

Rapid/dramatic response to low dose steroids

Reduce steroid dose over 18months - 24 months

19
Q

When may someone suffer from Fibromyalgia?

A

22-50 years old, after emotional or physical trauma

20
Q

What are the clinical features of fibromyalgia?

A

pain in neck, shoulders, lower back, and chest wall
Worse on exertion, fatigue and stress
sensation of swelling
Pins/needles, headaches, abdo pain (IBS), depression, poor concentration, memory

21
Q

What are the treatments of fibromyalgia?

A

Physical and mental therapy,
analgesia
Gabapentin and pregabalin

22
Q

What steroid dose is needed for polymyalgia?

A

15mg OD

MSK (15 decks)

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