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Flashcards in Muscle Disease Deck (22):
1

What is muscle pain?

Myalgia

2

How might a muscle disease present itself?

Myalgia, weakness/tiredness,
Stiffness
Abnormal blood tests

3

What are clinical features of Idiopathic Inflammatory Myopathies?

muscle weakness,
insidious onset
symmetrical, proximal muscles
sturggle with tasts e.g.difficulty brushing hair

4

What are indications of Dermatomyositis ?

Gottrons sign
Heliotrope rash
Shawl sign

5

What other organs are involved with Dermatomyositis?

Lung (ILD)
Oesophagus (Dysphagia)
Heart (myocarditis)

6

Name two tests that can be done, and what are they?

1. Confrontational testing - direct testing of power
2. Isotonic testing - 30 second sit to stand test

7

What drugs can be used to treat Dermatomyositis

Glucocorticoids
Azathioprine
Methotrexate
Ciclosporin
IV immunoglobulin

8

What can Inclusion body myositis be misdiagnosed as?

Polymyositis

9

Who's more likely to get Inclusion body myositis ?

>50's

10

What drug can cause muscle pain?

Statin

11

What is the clinical appearance of Inclusion body myositis ?

More insidious onset
Distal muscle weakeness
Weakness in wrist, finger flexors in upper limbs and quads an anterior tibial muscles in legs

12

What does a muscle biopsy of Inclusion body myositis show?

Inclusion bodies

13

Who is more likely to suffer from Polymyalgia Rheumatica?

>50's

14

What are the clinical features of Polymyalgia Rheumatica?

Shoulder and hip girdle pain
morning stiffness
fatigue, anorexia, weight loss, and fever
reduced shoulder, neck and hip movement
Muscle strength is NORMAL

15

What is another name for Temporal Arthritis?

Giant cell arhtritis

16

What occurs with Temporal Arthritis ?

Headache
Scalp tenderness
Jaw claudication
Visual loss (amaurosis fugax)
Tender, enlarged and non-pulsatile temporal arteries

17

What investigation results are found with temporal arthritis?

Raised ESR
Plasma viscosity
CRP

18

What is the treatment for temporal arthritis?

Rapid/dramatic response to low dose steroids
Reduce steroid dose over 18months - 24 months

19

When may someone suffer from Fibromyalgia?

22-50 years old, after emotional or physical trauma

20

What are the clinical features of fibromyalgia?

pain in neck, shoulders, lower back, and chest wall
Worse on exertion, fatigue and stress
sensation of swelling
Pins/needles, headaches, abdo pain (IBS), depression, poor concentration, memory

21

What are the treatments of fibromyalgia?

Physical and mental therapy,
analgesia
Gabapentin and pregabalin

22

What steroid dose is needed for polymyalgia?

15mg OD