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Flashcards in Insomnia Deck (23):
1

Indication: short term insomnia treatment

ADEs

Indication
- Avoid use more than 3 wks
- Start with lowest effective dose
- Taper slowly if longer use

ADEs
- Daytime somnolence
- Amnesia
- Early morning insomnia
- Daytime anxiety, confusion, sleep driving
- Ataxia and falls in elderly

2

Ambien

- MOA
- Dose/Form

Zopidem

- MOA: Short acting non-bzn hypnotic agents
- Dose: 10 mg QHS. Elderly 2.5 to 5mg PO QHS

3

Edluar

- Form

Zolpidem

- Form: 5 -10mg SL tab.
Place under the tongue.
No water or meal within 20min

4

ZolpiMist

- Form

Zolpidem

- Dose: 5-10mg spray over the tongue

5

Intermezzo

- Indicaiton
- Form
- Dose: for men and women

Zolpidem

- Indication: for insomnia ass with middle of the night awakening. Take only if there are 4 hrs remaining b/4 wake time
- Form: SL
- Dose: 1.75mg (women) and 3.5(men)

6

Sonata

- Dose
- Half life
- Metabolize

Zaleplon

- Dose: Star 5-10mg. Max 20mg. Elderly 5mg QHS
- Half life: 1H => shortest half life
- Metabolize: CYP3A4

7

Restoril

- MOA
- Given:

Temazepam

- MOA: Benzo
- Dose: 15min b/4 bedtime

8

Prosom

- MOA
- Dose

Estazolam

- MOA: Benzo
- Dose: 15min before bedtime

9

Adapin

- Class
- Indication
- ADEs

Doxepin

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover

10

Elavil

- Class
- Indication
- ADE
- Avoid

Amitriptiline

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover
- Avoid: in elderly due to anticholinergic SEs

11

Desyrel

- Class
- Indication
- ADEs

Trazadone

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover

12

Remeron

- Class
- Indication
- ADEs

Mirtazepine

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover, wt gain, sedation

13

Benadryl

- Dose
- ADE

Diphenhydramine

- Dose: 25-50mg QHS
- ADEs: anticholinergic, paradoxical CNS agitation, exacerbates restless leg syndrome

14

Unisom

- Dose
- ADEs

Doxylamine

- Dose: 25-50mg QHS
- ADEs: anticholinergic, paradoxical CNS agitation, exacerbates restless leg syndrome

15

Vistaril

- Dose
- ADEs

Hydroxyzine

- Dose: 25-50mg QHS
- ADEs: anticholinergic, paradoxical CNS agitation, exacerbates restless leg syndrome

16

Melatonin

Melatonin

17

Rozerem

- MOA
- Dose
- Avoid

Ramelteon

- MOA: melatonin receptor agonist
- Dose: 8mg PO QHS within 30 b/4 bedtime.
- Avoid: give after a high fat meal and liver disease

18

Valerian root

Valerian root

19

Sinequan

- Class
- Indication
- ADEs

Doxepin

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover

20

Silenor

- Class
- Indication
- ADEs

Doxepin

- Class: antidepressants
- Indication: major depression, hyperactivity hx PLUS insomnia
- ADEs: anticholinergic, AM hangover

21

Hetlioz

- Indication
- Administration

Tasimelteon

- Indication: Melatonin receptor agonist for non-24H sleep awake disorder in BLIND patients
- Administration: take without food

22

Lunesta

Eszopiclone

23

Belsomra

- MOA
- Indication
- Administration
- CS

Suvorexant

- MOA: Orexin receptor antagonist
- I: insomnia
- Administration: take only if there are 7H remaining
- CS-IV