Flashcards in Integumentary System I and II Deck (79)
What are the essential functions of the integumentary system?
what type of epithelium makes up the epidermis?
keratinized stratified squamous epithelium
what is the epidermis derived from?
what type of tissue is the dermis made of?
what is the dermis derived from?
what type of cells make up the stratum corneum?
what is eleiden?
protein similar to keratin - transformation product of keratonhyalin
what type of skin is stratum lucidum found in?
thick skin only
what type of cells are found in the stratum basale?
mitotically active cells
what layers make up the stratum malpighii?
basale and spinosum
what type of cells make up the single layer of cells found in the stratum basale?
small, cuboidal to low columnar
how do the cells of the stratum basale attach to ECM while resting on basal lamina?
what type of granules are found in the stratum granulosum?
what is Parakeratosis?
keratin layer is abnormal - contains nuclear remnants
what is acanthusis?
abnormal epidermal thickening
- due to increase depth of stratum spinosum
common feature of many skin conditions
what layers make up the dermis?
what type of CT is found in papillary layer?
what type of CT is found in reticular layer?
what is the main cell type of epidermis?
what are the cells of the epidermis?
what type of cells Langerhan's cells?
antigen presenting cells
what types of cells are merkel cells?
What are the two essentials activities of keratinocytes?
epidermal water barrier formation
what do keratohyalin granules contain?
intermediate filament associated proteins = filaggrin
what are tonofilaments?
intermediate filaments = keratin filaments
what are tonofibrils?
bundles of tonofilaments
what is the ABCD rule of Malignant melanoma?
Border is irregular
where are the melanocytes in light skin?
concentrated near basal layer
where are the melanocytes in dark skin?
throughout the epidermis