Integumentary System I and II Flashcards Preview

Histology Post Midterm > Integumentary System I and II > Flashcards

Flashcards in Integumentary System I and II Deck (79)
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1

What are the essential functions of the integumentary system?

barrier
immunologic
homeostasis
sensory
endocrine
excretion

2

what type of epithelium makes up the epidermis?

keratinized stratified squamous epithelium

3

what is the epidermis derived from?

ectoderm

4

what type of tissue is the dermis made of?

dense CT

5

what is the dermis derived from?

mesoderm

6

what type of cells make up the stratum corneum?

keratinized cells

7

what is eleiden?

protein similar to keratin - transformation product of keratonhyalin

8

what type of skin is stratum lucidum found in?

thick skin only

9

what type of cells are found in the stratum basale?

mitotically active cells

10

what layers make up the stratum malpighii?

basale and spinosum

11

what type of cells make up the single layer of cells found in the stratum basale?

small, cuboidal to low columnar

12

how do the cells of the stratum basale attach to ECM while resting on basal lamina?

hemidesmosomes

13

what type of granules are found in the stratum granulosum?

keratohyalin granules

14

what is Parakeratosis?

keratin layer is abnormal - contains nuclear remnants

15

what is acanthusis?

abnormal epidermal thickening
- due to increase depth of stratum spinosum
common feature of many skin conditions

16

what layers make up the dermis?

papillary layer
reticular layer

17

what type of CT is found in papillary layer?

loose CT

18

what type of CT is found in reticular layer?

dense CT

19

what is the main cell type of epidermis?

keratinocytes

20

what are the cells of the epidermis?

keratinocytes
melanocytes
langerhan's cells
merkel cells

21

what type of cells Langerhan's cells?

antigen presenting cells

22

what types of cells are merkel cells?

cutaneous sensation

23

What are the two essentials activities of keratinocytes?

produce keratin
epidermal water barrier formation

24

what do keratohyalin granules contain?

intermediate filament associated proteins = filaggrin
trichohyalin

25

what are tonofilaments?

intermediate filaments = keratin filaments

26

what are tonofibrils?

bundles of tonofilaments

27

what is the ABCD rule of Malignant melanoma?

Asymmetrical
Border is irregular
Color variation
Diameter

28

where are the melanocytes in light skin?

concentrated near basal layer

29

where are the melanocytes in dark skin?

throughout the epidermis

30

in what skin is melanocyte degradation more rapid?

light skin