Integumentary Terms (Path Final) Flashcards Preview

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Flashcards in Integumentary Terms (Path Final) Deck (113):
1

Acantholysis

loss of cohesion btwn keratinocytes caused by the breakdown of intercellular bridges

2

Acanthosis

thickening of the spinous cell layer (stratum spinosum) of the epidermis

3

Acral

distal parts of the extremities

4

Anagen

phase in which hair synthesis takes place

5

Anaplasia

lack of cellular differentiation & organization, a feature of neoplastic cells

6

Angioedema

vascular reaction involving the deep dermis or subcutis & consistitng of edema manifested as giant wheals & caused by dilation & increased permeability of capillaries

7

Angioedema is a deeper version of what?

Urticaria

8

Ballooning degeneration

marked intracellular fluid accumulation in the cells of the epidermis

9

Blister

localized collection of fluid usually in or beneath the epidermis

10

A blister is also known as what? (2)

vesicle or bulla

11

Bulla

Blister > or = to 1.0 cm

12

Carinoma in situ

malignant neoplasm of epithelial origin that has not invaded through the basement membrane

13

Catagen

Transition phase of the hair cyle; btwn growth & resting phase

14

Cellulitis

acute bacT infection of the dermis & subcutis that spreads to surrounding soft tissues

15

What are the characteristics of Cellulitis? (6)

erythema
warmth
swelling
pain
fever
enlarged lymph nodes

16

What is often the source of infection for Cellulitis?

penetrating wound in the area of infection

17

Comedo (pl= comedones)

plug of follicular stratum corneum & dried sebum in a hair follicle that leads to follicular distention

18

Cornification

Production of stratum corneum by terminal epidermal differentiation

19

Material formed by drying of exudate or secretion on the skin surface

crust

20

Small molecular wt. protein (< 30 kD) that are mediators of inflammation & growth

Cytokines

21

Naturally pigmented black or brown mycelium or conidium

Dematiaceous

22

Infection of the stratum corneum of the epidermis, hair or claws with fungi of the genera Microsporum, Epidermophyton, or Trichophyton

Dermatophytosis

23

Noninflammatory lesion of the skin

Dermatosis

24

Dandruff

Detritus

25

Abnormal, premature or imperfect keratinization

Dyskeratosis

26

Abnormal development

Dysplasia

27

Shedding of hair

Effluvium

28

Degeneration of dermal C.T. leading to accumulation of elastotic fibers

Elastosis

29

When is elastosis sometimes seen?

w/ solar dermatitis

30

peripheral expanding ring of scale

Epidermal Collarette

31

Inflammation of the epidermis

Epidermitis

32

Separation of the epidermis from the dermis

Epidermolysis

33

Have a predilection to enter the epidermis or other epithelial structures as seen with cutaneous T-cell lymphoma (mycosis fungoides)

Epidermotropic or Epitheliotropic

34

Loss of the superficial layers of the epidermis

Erosion

35

Rapid development of skin lesion associated w/ redness

Eruption

36

Redness of the skin caused by congestion of capillaries

Erythema

37

Superficial loss of epidermal layers caused by physical trauma (scratching)

Excoriation

38

Shedding of layers or scales

Exfoliation

39

Stage in which old hairs are shed in the hair cycle

Exogen

40

Fluid, cells or debris from blood vessels deposited in or on other tissues

Exudate

41

Cleft or groove

Fissure

42

Inflammation of a hair follicle

Folliculitis

43

Circumscribed, painful node (accumulation of pus) in the dermis 2ry to follicular rupture

Furuncle

44

Rupture of follicles usually caused by inflammation, distention &/or trauma to entry of follicular contents into the dermis

Furunculosis

45

A genetically determined disorder of the skin

Genodermatosis

46

smooth skin, hairless skin

Glabrous

47

A localized, tumor-like malformation of mature cells & tissue that includes normal components of the organ in which the hamartoma arises but that is disorganized, present in excess & sometimes larger than normal.

Hamartoma

48

Is a hamartoma a true neoplasm?

No, b/c it involves the proliferation of more than one cell type & often includes the development of complex structures such as arteries or follicles

49

Intracellular fluid accumulation in cells of the basal epidermis

Hydropic degeneration

50

Thickening of the stratum corneum

Hyperkeratosis

51

Incomplete development

Hypoplasia

52

Less hair than normal

Hypotrichosis

53

Congenital skin disorder in which the skin is thickened by scales (hyperkeratosis) that can crack into plates resembling fish scales

Ichthyosis

54

Bacterial dermatitis characterized by pustules

Impetigo

55

Slow growing; persistent ulcers on the lips of cats

Indolent

56

Hardening of the skin as a result of inflammation or fibrosis

Indurated

57

Inflammation arranged in a layer close to & often obscurring the epidermal-dermal jxn & w/ vacuolated & sometimes apoptotic basal cells. Can be mild or extensive

Interface

58

Dermatitis that develops b/c of friction btwn apposing skin surfaces

Intertrigo

59

Epidermal cells that synthesize keratin & comprise more than 90% of epidermal cells

Keratinocytes

60

Uncommon to rare circumscribed paular, plaque-like, or linear focus of proliferative keratinocytes covered by thick stratum corneum

Keratosis (pl. Keratoses)

61

What can cause keratosis? (2)

Sun exposure
Idiopathic

62

An intense focal folliculitis usually caused by a dermatophyte infection

Kerion

63

Intraepidermal dendritic APCs

Langerhans' cells

64

Thickening of skin w/ accentuation of skin creases caused by marked acanthosis

Lichenification

65

Generally refers to a dense zone of dermal inflammation parallel to the epidermis usually w/o basal cell injury

Lichenoid

66

Uncommon to rare, often idiopathic, single or grouped papules, plaques or papillomatous foci covered by scale

Lichenoid dermatosis

67

Histologically composed of epidermal hyperplasia, lichenoid lymphoplasmacytic dermal inflammation, hyperkeratosis & parakeratosis

Lichenoid dermatosis

68

Flat, circumscribed lesion of altered skin color

Macule

69

Dark granular pigment produced by melanocytes that is responsible for the brown coloration of hair, skin & other tissues

Melanin

70

Macrophage containing ingested melanin

Melanophage

71

A neuroendocrine cell found in the stratum basale

Merkel Cell

72

Glycosaminoglycan (GAG), normal component of intercellular ground substance of the deris; consists of protein bound to hyaluronic acid

Mucin

73

A mass of hyphae

Mycelium

74

Slowly progressive infection of the cutaneous & SQ tissue, fascia & sometimes underlying bone caused by traumatic implantation of actinomycetes or fungi

Mycetoma

75

Traumatic implantation of actinomycetes

Actinomycotic mycetoma

76

Traumatic implantation of fungi

Eumycotic mycetoma

77

Non-pitting edema of the skin b/c of abnormal deposits of mucin in the dermis

Myxedema

78

Ac acute lif-threatening subtype of cellulitis usually caused by Strep. infection & toxin production. Located w/in the SQ fat & fascial planes

Necrotizing fasciitis

79

What are the appearance of the gross lesions of necrotizing fasciitis?

Painful, hot & swollen areas w/ entensive exudation & necrosis

80

What can Necrotizing fasciitis progress to?

can progress rapidly to shock

81

Circumscribed malformation of the skin assumed to be of congenital or inherited origin & consisting of any component of the skin

Nevus

82

Which term is preferred over nevus?

Hamartoma

83

A circumscribed, solid elevation of skin (> 1cm)

Nodule

84

Abnormal formation of the claw

Onychodystrophy

85

Sloughing of the claws

Oncychomadesis

86

Inflammation of SQ adipose tissue

Panniculitis

87

Circumscribed, solid elevation of skin (< 1cm)

Papule

88

Retention of pyknotic nuclei in epidermal cells of the stratum corneum

Parakeratosis

89

Inflammation of skin around the claws

Paronychia

90

A localized intraepidermal collection of neoplastic lymphocytes characterisitic of epitheliotropuc lymphoma (mycosis fungoides)

Pautrier's Microabscess

91

A group of cutaneous dz's associated w/ blistering

Pemphigus

92

Mycotic dz caused by pigmented fungi of a variety of genera & species that do not form sclerotic bodies or gransules

Phaeohyphomycosis

93

Melanin pigment w/in dermal macrophages or free in the dermis developing via injury to pigment containing basal layer cells

Pigmentary Incontinence

94

Flat-topped, solid elevation in the skin that occupies a relatively large surface area in comparison w/ its height (> 1 cm)

Plaque

95

Itching

Pruritus

96

Small, circumscribed accumulation of pus w/in the epidermis or w/in a hair follicle

Pustule

97

Pyogenic bacterial infection of the skin

Pyoderma

98

Term from human med; used to define an ulcerative basal cell carcinoma

Rodent ulcer

99

Which term is often incorrectly used in Vet Med to describe an indolent ulcer affecting the lips of cats?

Rodent Ulcer

100

Thin, platelike accumulation of stratum corneum on the surface of the skin

Scale

101

Nonspecific term for C.S. of scaling, crusting & greasiness

Seborrhea

102

More specific term, applied to inherited cornification disorders

Primary seborrhea

103

Secretion of the sebaceous glands

Sebum

104

Intercellular edema, which, by widening of the intercellular space & stretching of the "intercellular bridges" creates a sponge-like appearance to the epidermis

Spongiosis

105

Resting phase of the hair cycle

Telogen

106

Full thickness loss of the epidermis w/ extension into the dermis

Ulcer

107

Usually transient vascular rxn in the upper dermis consisting of edema manifested clinically as wheals; more superficial version of angioedema

Urticaria

108

What is another term for wheals?

Hives

109

Small blister w/in the epidermis or at or below the dermal-epidermal interface (<1.0 cm)

Vesicle

110

Long, coarse hair located above the nose

Vibrissa

111

Acquired disorder characterized by circumscribed areas of depigmentation in the skin

Vitilido

112

Smooth, circumscribed, slightly elevated area on the skin caused by dermal edema

Wheal

113

Unicellular budding fungus

Yeast